Literature DB >> 1996978

Animal model of systemic carnitine deficiency: analysis in C3H-H-2 degrees strain of mouse associated with juvenile visceral steatosis.

M Kuwajima1, N Kono, M Horiuchi, Y Imamura, A Ono, Y Inui, S Kawata, T Koizumi, J Hayakawa, T Saheki.   

Abstract

We analyzed carnitine profiles in C3H-H-2 degrees strain of mouse associated with fatty liver, hyperammonemia and hypoglycemia (Koizumi et al., 1988). Carnitine levels in serum, liver and muscle of mouse with fatty liver were markedly decreased in comparison with those of control mouse (littermates without fatty liver). This is a useful animal model to analyze the role of carnitine in lipid, amino acid and carbohydrate metabolism.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1996978     DOI： 10.1016/0006-291x(91)91532-h

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  15 in total

1.  Mapping of jvs (juvenile visceral steatosis) gene, which causes systemic carnitine deficiency in mice, on chromosome 11.

Authors:  H Nikaido; M Horiuchi; N Hashimoto; T Saheki; J Hayakawa
Journal:  Mamm Genome       Date:  1995-05       Impact factor: 2.957

Review 2.  On the molecular etiology of decreased arachidonic (20:4n-6), docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids in Zellweger syndrome and other peroxisomal disorders.

Authors:  J P Infante; V A Huszagh
Journal:  Mol Cell Biochem       Date:  1997-03       Impact factor: 3.396

3.  Hyperammonemia in carnitine-deficient adult JVS mice used by starvation.

Authors:  Xiang Xian Li; Keiko Kobayashi; Masahisa Horiuchi; Abdul Jalil; Goichiro Yoshida; Takeyori Saheki
Journal:  Metab Brain Dis       Date:  2002-12       Impact factor: 3.584

Review 4.  A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation.

Authors:  Sander Michel Houten; Ronald J A Wanders
Journal:  J Inherit Metab Dis       Date:  2010-03-02       Impact factor: 4.982

Review 5.  Carnitine transport: pathophysiology and metabolism of known molecular defects.

Authors:  I Tein
Journal:  J Inherit Metab Dis       Date:  2003       Impact factor: 4.982

6.  Cardiomyopathy and carnitine deficiency.

Authors:  Cristina Amat di San Filippo; Matthew R G Taylor; Luisa Mestroni; Lorenzo D Botto; Nicola Longo
Journal:  Mol Genet Metab       Date:  2008-03-11       Impact factor: 4.797

7.  Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation.

Authors:  Jisong Peng; Long Yu; Masahisa Horiuchi; Pingzhao Zhang; Xinghua Huang; Yazhou Zhang; Dan Li; Md Abdul Jalil; Shouyyan Zhao
Journal:  Mol Biol Rep       Date:  2002-12       Impact factor: 2.316

8.  Evidence for linkage of human primary systemic carnitine deficiency with D5S436: a novel gene locus on chromosome 5q.

Authors:  Y Shoji; A Koizumi; T Kayo; T Ohata; T Takahashi; K Harada; G Takada
Journal:  Am J Hum Genet       Date:  1998-07       Impact factor: 11.025

9.  Mitochondrial abnormalities of muscle tissue in mice with juvenile visceral steatosis associated with systemic carnitine deficiency.

Authors:  J Miyagawa; M Kuwajima; T Hanafusa; K Ozaki; H Fujimura; A Ono; R Uenaka; I Narama; T Oue; K Yamamoto
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

Review 10.  Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

Authors:  Quentin M Anstee; Robert D Goldin
Journal:  Int J Exp Pathol       Date:  2006-02       Impact factor: 1.925
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.