Literature DB >> 1996973

Accumulation and metabolism of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 in muscarinic-receptor-stimulated SH-SY5Y neuroblastoma cells.

D G Lambert1, R A Challiss, S R Nahorski.   

Abstract

Stimulation of M3 muscarinic receptors expressed by SH-SY5Y cells induced a dose- and time-related increase in the mass of Ins(1,4,5)P3 (basal 38.3 +/- 5.8 pmol/mg of protein) and Ins(1,3,4,5)P4 (basal 6.1 +/- 1.2 pmol/mg of protein). Comparison of radioreceptor mass assays with [3H]inositol labelling showed higher-fold stimulations with the former protocol. The later accumulation of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 mass was dependent upon extracellular Ca2+.

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Year:  1991        PMID： 1996973      PMCID： PMC1149832          DOI： 10.1042/bj2730791

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  27 in total

1.  A putative M3 muscarinic cholinergic receptor of high molecular weight couples to phosphoinositide hydrolysis in human SK-N-SH neuroblastoma cells.

Authors:  S K Fisher; A M Heacock
Journal:  J Neurochem       Date:  1988-03       Impact factor: 5.372

2.  Mass measurements of inositol(1,4,5)trisphosphate in rat cerebral cortex slices using a radioreceptor assay: effects of neurotransmitters and depolarization.

Authors:  R A Challiss; I H Batty; S R Nahorski
Journal:  Biochem Biophys Res Commun       Date:  1988-12-15       Impact factor: 3.575

Review 3.  Metabolism of the inositol phosphates produced upon receptor activation.

Authors:  S B Shears
Journal:  Biochem J       Date:  1989-06-01       Impact factor: 3.857

Review 4.  Inositol polyphosphates and neuronal calcium homeostasis.

Authors:  S R Nahorski
Journal:  Trends Neurosci       Date:  1988-10       Impact factor: 13.837

5.  Inositol 1,3,4,5-tetrakisphosphate-induced release of intracellular Ca2+ in SH-SY5Y neuroblastoma cells.

Authors:  D J Gawler; B V Potter; S R Nahorski
Journal:  Biochem J       Date:  1990-12-01       Impact factor: 3.857

6.  Muscarinic receptor regulation of cytoplasmic Ca2+ concentrations in human SK-N-SH neuroblastoma cells: Ca2+ requirements for phospholipase C activation.

Authors:  S K Fisher; L M Domask; R M Roland
Journal:  Mol Pharmacol       Date:  1989-02       Impact factor: 4.436

7.  Chemoattractant receptor promotion of Ca2+ influx across the plasma membrane of HL-60 cells. A role for cytosolic free calcium elevations and inositol 1,3,4,5-tetrakisphosphate production.

Authors:  D Pittet; D P Lew; G W Mayr; A Monod; W Schlegel
Journal:  J Biol Chem       Date:  1989-05-05       Impact factor: 5.157

8.  Accumulation of inositol polyphosphate isomers in agonist-stimulated cerebral-cortex slices. Comparison with metabolic profiles in cell-free preparations.

Authors:  I H Batty; A J Letcher; S R Nahorski
Journal:  Biochem J       Date:  1989-02-15       Impact factor: 3.857

9.  Generation of inositol phosphates, cytosolic Ca2+, and ionic fluxes in PC12 cells treated with bradykinin.

Authors:  C Fasolato; A Pandiella; J Meldolesi; T Pozzan
Journal:  J Biol Chem       Date:  1988-11-25       Impact factor: 5.157

10.  Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.

Authors:  M J Berridge; R M Dawson; C P Downes; J P Heslop; R F Irvine
Journal:  Biochem J       Date:  1983-05-15       Impact factor: 3.857
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  10 in total

1.  Elevation of cytosolic calcium by cholinoceptor agonists in SH-SY5Y human neuroblastoma cells: estimation of the contribution of voltage-dependent currents.

Authors:  I D Forsythe; D G Lambert; S R Nahorski; P Lindsdell
Journal:  Br J Pharmacol       Date:  1992-09       Impact factor: 8.739

2.  Interactions between inositol tris- and tetrakis-phosphates. Effects on intracellular Ca2+ mobilization in SH-SY5Y cells.

Authors:  D J Gawler; B V Potter; R Gigg; S R Nahorski
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

3.  Tissue- and cell-specific expression of Ins(1,4,5)P3 3-kinase isoenzymes.

Authors:  V Vanweyenberg; D Communi; C S D'Santos; C Erneux
Journal:  Biochem J       Date:  1995-03-01       Impact factor: 3.857

4.  Stimulation of tyrosine phosphorylation and mitogen-activated-protein (MAP) kinase activity in human SH-SY5Y neuroblastoma cells by carbachol.

Authors:  S Offermanns; E Bombien; G Schultz
Journal:  Biochem J       Date:  1993-09-01       Impact factor: 3.857

5.  Activation of phospholipase C in SH-SY5Y neuroblastoma cells by potassium-induced calcium entry.

Authors:  D Smart; A Wandless; D G Lambert
Journal:  Br J Pharmacol       Date:  1995-09       Impact factor: 8.739

6.  Different pathways of inositol phosphate metabolism in intact neonatal rat hearts and isolated cardiomyocytes.

Authors:  E A Woodcock; J K Tanner; M Fullerton; I J Kuraja
Journal:  Biochem J       Date:  1992-02-01       Impact factor: 3.857

7.  Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells.

Authors:  G V Los; I P Artemenko; L E Hokin
Journal:  Biochem J       Date:  1995-10-01       Impact factor: 3.857

8.  Studies on the mechanism of [3H]-noradrenaline release from SH-SY5Y cells: the role of Ca2+ and cyclic AMP.

Authors:  R Atcheson; D G Lambert; R A Hirst; D J Rowbotham
Journal:  Br J Pharmacol       Date:  1994-03       Impact factor: 8.739

9.  Characterization of the effects of lithium on phosphatidylinositol (PI) cycle activity in human muscarinic m1 receptor-transfected CHO cells.

Authors:  J R Atack; A M Prior; D Griffith; C I Ragan
Journal:  Br J Pharmacol       Date:  1993-10       Impact factor: 8.739

10.  Quantitative comparisons of muscarinic and bradykinin receptor-mediated Ins (1,4,5)P3 accumulation and Ca2+ signalling in human neuroblastoma cells.

Authors:  G B Willars; S R Nahorski
Journal:  Br J Pharmacol       Date:  1995-03       Impact factor: 8.739
  10 in total

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