| Literature DB >> 19969045 |
Ying Wang1, Hongping Yin, Xiaobo Lv, Yufeng Wang, Hongyan Gao, Min Wang.
Abstract
A water-soluble polysaccharide (CPS-2), isolated from the cultured Cordyceps sinensis, was obtained by hot-water extraction, anion-exchange and gel permeation chromatography. Its structural characteristics were investigated by PMP pre-column derivation, periodate oxidation, methylation analysis, FTIR and NMR spectroscopy. CPS-2 was found to be mostly of alpha-(1-->4)-D-glucose and alpha-(1-->3)-D-mannose, branched with alpha-(1-->4,6)-D-glucose every twelve residues on average. CPS-2 had a molecular weight of 4.39x10(4) Da. The protective effect of CPS-2 on the model of chronic renal failure was established by fulgerizing kidney. The changes in blood urea nitrogen and serum creatinine revealed that CPS-2 could significantly relieve renal failure caused by fulgerizing kidney. Copyright 2009 Elsevier B.V. All rights reserved.Entities:
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Year: 2009 PMID： 19969045 DOI： 10.1016/j.fitote.2009.11.008
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882