Literature DB >> 19967328

[The impact of silicone spray on scar formation. A single-center placebo-controlled double-blind trial].

I Stoffels1, T P Wolter, A M Sailer, N Pallua.   

Abstract

For more than two decades silicone has successfully been employed in the treatment and prevention of hypertrophic scars and keloids as a painless noninvasive modality with few side effects. In the present trial, after 3 months of treatment the Patient Scar Assessment Scale demonstrated that patient satisfaction with the silicone application was significantly higher compared to placebo. When treatment was stopped after 3 months, the topical silicone spray did not exhibit any lasting long-term impact on the objective results of scar formation. Due to the significant differences in patient satisfaction once treatment has ended and since the administration is safe and simple, any final decision on treatment indication should be tailored to the patient and include the psychological well-being of the patient as well as the temporary improvement in scar formation during treatment.

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Year:  2010        PMID: 19967328     DOI: 10.1007/s00105-009-1886-y

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  27 in total

1.  Rating the resolving hypertrophic scar: comparison of the Vancouver Scar Scale and scar volume.

Authors:  B Nedelec; H A Shankowsky; E E Tredget
Journal:  J Burn Care Rehabil       Date:  2000 May-Jun

Review 2.  International clinical recommendations on scar management.

Authors:  Thomas A Mustoe; Rodney D Cooter; Michael H Gold; F D Richard Hobbs; Albert-Adrien Ramelet; Peter G Shakespeare; Maurizio Stella; Luc Téot; Fiona M Wood; Ulrich E Ziegler
Journal:  Plast Reconstr Surg       Date:  2002-08       Impact factor: 4.730

Review 3.  Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.

Authors:  L O'Brien; A Pandit
Journal:  Cochrane Database Syst Rev       Date:  2006-01-25

4.  Prospective, single-blind, randomized, controlled study to assess the efficacy of the 585-nm flashlamp-pumped pulsed-dye laser and silicone gel sheeting in hypertrophic scar treatment.

Authors:  G P Wittenberg; B G Fabian; J L Bogomilsky; L R Schultz; E J Rudner; M L Chaffins; G M Saed; R L Burns; D P Fivenson
Journal:  Arch Dermatol       Date:  1999-09

5.  Silicone versus nonsilicone gel dressings: a controlled trial.

Authors:  G V de Oliveira; T A Nunes; L A Magna; M L Cintra; G T Kitten; S Zarpellon; C M Raposo Do Amaral
Journal:  Dermatol Surg       Date:  2001-08       Impact factor: 3.398

6.  Silicone cream occlusive dressing--a novel noninvasive regimen in the treatment of keloid.

Authors:  T W Wong; H C Chiu; C H Chang; L J Lin; C C Liu; J S Chen
Journal:  Dermatology       Date:  1996       Impact factor: 5.366

7.  The patient and observer scar assessment scale: a reliable and feasible tool for scar evaluation.

Authors:  Lieneke J Draaijers; Fenike R H Tempelman; Yvonne A M Botman; Wim E Tuinebreijer; Esther Middelkoop; Robert W Kreis; Paul P M van Zuijlen
Journal:  Plast Reconstr Surg       Date:  2004-06       Impact factor: 4.730

8.  Cica-Care gel sheeting in the management of hypertrophic scarring.

Authors:  S A Carney; C G Cason; J P Gowar; J H Stevenson; J McNee; A R Groves; S S Thomas; N B Hart; P Auclair
Journal:  Burns       Date:  1994-04       Impact factor: 2.744

9.  Effect of Mederma on hypertrophic scarring in the rabbit ear model.

Authors:  Alexandrina S Saulis; Jon H Mogford; Thomas A Mustoe
Journal:  Plast Reconstr Surg       Date:  2002-07       Impact factor: 4.730

10.  Hypertrophic sternal scars: silicone gel sheet versus Kenalog injection treatment.

Authors:  J E Sproat; A Dalcin; N Weitauer; R S Roberts
Journal:  Plast Reconstr Surg       Date:  1992-12       Impact factor: 4.730

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  3 in total

Review 1.  Silicone gel sheeting for treating hypertrophic scars.

Authors:  Qingling Jiang; Junjie Chen; Fan Tian; Zhenmi Liu
Journal:  Cochrane Database Syst Rev       Date:  2021-09-26

2.  Management of keloids and hypertrophic scars: current and emerging options.

Authors:  Gerd G Gauglitz
Journal:  Clin Cosmet Investig Dermatol       Date:  2013-04-24

Review 3.  Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.

Authors:  Lisa O'Brien; Daniel J Jones
Journal:  Cochrane Database Syst Rev       Date:  2013-09-12
  3 in total

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