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Literature DB >> 19966770

Quelling cholesterol pathway fends off brain damage.

Maria T Bengoechea-Alonso, Johan Ericsson.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 2009 PMID： 19966770 DOI： 10.1038/nm1209-1358

Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440

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12 in total

1. Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1.

Authors: Joon No Lee; Jin Ye
Journal: J Biol Chem Date: 2004-08-10 Impact factor: 5.157

Review 2. Protein sensors for membrane sterols.

Authors: Joseph L Goldstein; Russell A DeBose-Boyd; Michael S Brown
Journal: Cell Date: 2006-01-13 Impact factor: 41.582

3. Cdk1/cyclin B-mediated phosphorylation stabilizes SREBP1 during mitosis.

Authors: Maria T Bengoechea-Alonso; Johan Ericsson
Journal: Cell Cycle Date: 2006-08-01 Impact factor: 4.534

Review 4. Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists.

Authors: Keith W Muir
Journal: Curr Opin Pharmacol Date: 2005-12-15 Impact factor: 5.547

Review 5. SREBP in signal transduction: cholesterol metabolism and beyond.

Authors: Maria T Bengoechea-Alonso; Johan Ericsson
Journal: Curr Opin Cell Biol Date: 2007-02-15 Impact factor: 8.382

6. Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries.

Authors: Changiz Taghibiglou; Henry G S Martin; Ted Weita Lai; Taesup Cho; Shiv Prasad; Luba Kojic; Jie Lu; Yitao Liu; Edmund Lo; Shu Zhang; Julia Z Z Wu; Yu Ping Li; Yan Hua Wen; Joon-Hyuk Imm; Max S Cynader; Yu Tian Wang
Journal: Nat Med Date: 2009-11-22 Impact factor: 53.440

7. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.

Authors: Shinji Kamisuki; Qian Mao; Lutfi Abu-Elheiga; Ziwei Gu; Akira Kugimiya; Youngjoo Kwon; Tokuyuki Shinohara; Yoshinori Kawazoe; Shin-ichi Sato; Koko Asakura; Hea-Young Park Choo; Juro Sakai; Salih J Wakil; Motonari Uesugi
Journal: Chem Biol Date: 2009-08-28

Quelling cholesterol pathway fends off brain damage.

1. Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1.

Review 2. Protein sensors for membrane sterols.

3. Cdk1/cyclin B-mediated phosphorylation stabilizes SREBP1 during mitosis.

Review 4. Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists.

Review 5. SREBP in signal transduction: cholesterol metabolism and beyond.

6. Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries.

7. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.

Review 8. The dichotomy of NMDA receptor signaling.

9. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis.

Review 10. SREBP-1c transcription factor and lipid homeostasis: clinical perspective.

1. Interactions of Aromatase and Seladin-1: A Neurosteroidogenic and Gender Perspective.