Literature DB >> 19966476

Identification and characterization of an Ecl1-family gene in Saccharomyces cerevisiae.

Kenko Azuma1, Hokuto Ohtsuka, Satoka Mita, Hiroshi Murakami, Hirofumi Aiba.   

Abstract

We found that YGR146C of Saccharomyces cerevisiae encodes a functional homolog of Ecl1 that is involved in the chronological lifespan of Schizosaccharomyces pombe. When YGR146C is overexpressed, it extends the viability of wild-type S. cerevisiae cells after entry into the stationary phase, as in the case of Ecl1. We propose that Ecl1 family proteins are novel regulatory factors involved in chronological lifespan among yeasts.

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Year:  2009        PMID: 19966476     DOI: 10.1271/bbb.90599

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  6 in total

1.  hsf1 (+) extends chronological lifespan through Ecl1 family genes in fission yeast.

Authors:  Hokuto Ohtsuka; Kenko Azuma; Hiroshi Murakami; Hirofumi Aiba
Journal:  Mol Genet Genomics       Date:  2010-11-12       Impact factor: 3.291

Review 2.  Aging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicans.

Authors:  Su-Ju Lin; Nicanor Austriaco
Journal:  FEMS Yeast Res       Date:  2013-11-08       Impact factor: 2.796

3.  Ecl1 is a zinc-binding protein involved in the zinc-limitation-dependent extension of chronological life span in fission yeast.

Authors:  Takafumi Shimasaki; Hokuto Ohtsuka; Chikako Naito; Kenko Azuma; Takeshi Tenno; Hidekazu Hiroaki; Hiroshi Murakami; Hirofumi Aiba
Journal:  Mol Genet Genomics       Date:  2017-02-03       Impact factor: 3.291

4.  Pma1, a P-type proton ATPase, is a determinant of chronological life span in fission yeast.

Authors:  Hirokazu Ito; Tomoko Oshiro; Yasuyuki Fujita; Sachiko Kubota; Chikako Naito; Hokuto Ohtsuka; Hiroshi Murakami; Hirofumi Aiba
Journal:  J Biol Chem       Date:  2010-09-09       Impact factor: 5.157

5.  Expression pattern and phenotypic characterization of the mutant strain reveals target genes and processes regulated by pka1 in the dimorphic fission yeast Schizosaccharomyces japonicus.

Authors:  László Papp; Matthias Sipiczki; Ida Miklós
Journal:  Curr Genet       Date:  2016-09-27       Impact factor: 3.886

6.  Sexual development of Schizosaccharomyces pombe is induced by zinc or iron limitation through Ecl1 family genes.

Authors:  Hokuto Ohtsuka; Maiko Ishida; Chikako Naito; Hiroshi Murakami; Hirofumi Aiba
Journal:  Mol Genet Genomics       Date:  2014-09-10       Impact factor: 3.291

  6 in total

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