Literature DB >> 19965579

Prelamin A prenylation and the treatment of progeria.

Howard J Worman1.   

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Year:  2009        PMID： 19965579      PMCID： PMC2803225          DOI： 10.1194/jlr.E004366

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


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  21 in total

1.  Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.

Authors:  Michael W Glynn; Thomas W Glover
Journal:  Hum Mol Genet       Date:  2005-08-26       Impact factor: 6.150

Review 2.  Farnesylated lamins, progeroid syndromes and farnesyl transferase inhibitors.

Authors:  Antonio E Rusiñol; Michael S Sinensky
Journal:  J Cell Sci       Date:  2006-08-15       Impact factor: 5.285

3.  Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science.

Authors:  Leslie B Gordon; Christine J Harling-Berg; Frank G Rothman
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2008-08       Impact factor: 6.053

4.  Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes.

Authors:  Julia I Toth; Shao H Yang; Xin Qiao; Anne P Beigneux; Michael H Gelb; Casey L Moulson; Jeffrey H Miner; Stephen G Young; Loren G Fong
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-29       Impact factor: 11.205

5.  A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.

Authors:  Shao H Yang; Margarita Meta; Xin Qiao; David Frost; Joy Bauch; Catherine Coffinier; Sharmila Majumdar; Martin O Bergo; Stephen G Young; Loren G Fong
Journal:  J Clin Invest       Date:  2006-08       Impact factor: 14.808

6.  Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Authors:  Ignacio Varela; Sandrine Pereira; Alejandro P Ugalde; Claire L Navarro; María F Suárez; Pierre Cau; Juan Cadiñanos; Fernando G Osorio; Nicolas Foray; Juan Cobo; Félix de Carlos; Nicolas Lévy; José M P Freije; Carlos López-Otín
Journal:  Nat Med       Date:  2008-06-29       Impact factor: 53.440

7.  Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated.

Authors:  Shao H Yang; Douglas A Andres; H Peter Spielmann; Stephen G Young; Loren G Fong
Journal:  J Clin Invest       Date:  2008-10       Impact factor: 14.808

8.  A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

Authors:  Loren G Fong; David Frost; Margarita Meta; Xin Qiao; Shao H Yang; Catherine Coffinier; Stephen G Young
Journal:  Science       Date:  2006-02-16       Impact factor: 47.728

Review 9.  "Laminopathies": a wide spectrum of human diseases.

Authors:  Howard J Worman; Gisèle Bonne
Journal:  Exp Cell Res       Date:  2007-03-30       Impact factor: 3.905

10.  Phenotype and course of Hutchinson-Gilford progeria syndrome.

Authors:  Melissa A Merideth; Leslie B Gordon; Sarah Clauss; Vandana Sachdev; Ann C M Smith; Monique B Perry; Carmen C Brewer; Christopher Zalewski; H Jeffrey Kim; Beth Solomon; Brian P Brooks; Lynn H Gerber; Maria L Turner; Demetrio L Domingo; Thomas C Hart; Jennifer Graf; James C Reynolds; Andrea Gropman; Jack A Yanovski; Marie Gerhard-Herman; Francis S Collins; Elizabeth G Nabel; Richard O Cannon; William A Gahl; Wendy J Introne
Journal:  N Engl J Med       Date:  2008-02-07       Impact factor: 91.245
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  4 in total

1.  Selective Gas-Phase Oxidation and Localization of Alkylated Cysteine Residues in Polypeptide Ions via Ion/Ion Chemistry.

Authors:  Alice L Pilo; Feifei Zhao; Scott A McLuckey
Journal:  J Proteome Res       Date:  2016-08-18       Impact factor: 4.466

2.  Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.

Authors:  Joshua D Ochocki; Mark D Distefano
Journal:  Medchemcomm       Date:  2013-03       Impact factor: 3.597

Review 3.  Recent Advances on the Structure and Function of RNA Acetyltransferase Kre33/NAT10.

Authors:  Sophie Sleiman; Francois Dragon
Journal:  Cells       Date:  2019-09-05       Impact factor: 6.600

4.  High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome.

Authors:  Juan A Fafián-Labora; Miriam Morente-López; Fco Javier de Toro; María C Arufe
Journal:  Int J Mol Sci       Date:  2021-07-07       Impact factor: 5.923
  4 in total

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