| Literature DB >> 19962662 |
Roberta Noberini1, Elena B Pasquale.
Abstract
Eph receptors are important but controversial regulators of cancer development. A recent study reported in Cell reveals that in the intestinal epithelium, EphB2 enhances proliferation through a kinase-dependent pathway and inhibits migration independent of its kinase activity. These separate pathways simultaneously promote proliferation but suppress invasive growth of intestinal adenomas.Entities:
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Year: 2009 PMID： 19962662 DOI： 10.1016/j.ccr.2009.11.008
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743