| Literature DB >> 19962660 |
Inma Martin Berenjeno1, Inma Martin-Berenjeno, Bart Vanhaesebroeck.
Abstract
The PI3K signaling axis is frequently activated in cancer resulting from inactivation of its negative regulator PTEN or activating mutations of the p110alpha catalytic subunit of PI3K. In this issue of Cancer Cell, Jaiswal et al. report that mutations in the p85alpha regulatory subunit of PI3K can also activate this pathway in cancer.Entities:
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Year: 2009 PMID： 19962660 DOI： 10.1016/j.ccr.2009.11.017
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743