Can vitamin D intake assist in improving the outcome of endodontic treatment for diabetic patients?

Diabetes mellitus is a common health problem with serious consequences. Researches suggested the relationship between diabetes and endodontic problems. Vitamin D has important biologic effects on glucose homeostasis, insulin release and response, and is considered to play a role in the pathogenesis of diabetes. Vitamin D can also influence the alveolar bone formation and inflammatory reactions in periradicular tissues. The hypothesis we proposed is that vitamin D may be beneficial to the prognosis of endodontic treatment for diabetic patients through two pathways. (c) 2009 Elsevier Ltd. All rights reserved.