BACKGROUND: Endometrial carcinoma is a relatively common condition which may occur with more than 6,400 new cases diagnosed each year in the UK (Cancer Research UK Statistics http://info.cancerresearchuk.org/cancerstats/types/uterus ). It may occur following hysterectomy especially if associated with prolonged hormone replacement therapy. CASE: We report the case of a 63-year-old lady who presented with a tumour in the sigmoid mesentery 13 years after hysterectomy and following 10 years of tamoxifen therapy for a breast carcinoma. This is the first time that endometrial cancer has been reported as a complication of tamoxifen therapy in the absence of a uterus. CONCLUSION: We suggest that endometrial carcinoma remains a differential diagnosis of any pelvic or abdominal mass even after hysterectomy, and a history of intake of oestrogen agonists and antagonists needs to be obtained.
BACKGROUND:Endometrial carcinoma is a relatively common condition which may occur with more than 6,400 new cases diagnosed each year in the UK (Cancer Research UK Statistics http://info.cancerresearchuk.org/cancerstats/types/uterus ). It may occur following hysterectomy especially if associated with prolonged hormone replacement therapy. CASE: We report the case of a 63-year-old lady who presented with a tumour in the sigmoid mesentery 13 years after hysterectomy and following 10 years of tamoxifen therapy for a breast carcinoma. This is the first time that endometrial cancer has been reported as a complication of tamoxifen therapy in the absence of a uterus. CONCLUSION: We suggest that endometrial carcinoma remains a differential diagnosis of any pelvic or abdominal mass even after hysterectomy, and a history of intake of oestrogen agonists and antagonists needs to be obtained.
Authors: Raquel P Dibi; Claudio G Zettler; Suzana A Pessini; Alice V Ayub; Suzane B de Almeida; Gustavo P G da Silveira Journal: Menopause Date: 2009 Mar-Apr Impact factor: 2.953
Authors: Mandana Saadat; Pauline T Truong; Hosam A Kader; Caroline H Speers; Eric Berthelet; Elissa McMurtrie; Ivo A Olivotto Journal: Cancer Date: 2007-07-01 Impact factor: 6.860