Literature DB >> 19958988

Impact of peripheral arterial disease on health status: a comparison with chronic heart failure.

Kim G Smolderen1, Aline J Pelle, Nina Kupper, Floortje Mols, Johan Denollet.   

Abstract

OBJECTIVE: To further document the experienced burden in patients with peripheral arterial disease (PAD), we compared the health status of patients with PAD and chronic heart failure (CHF). As a secondary aim, we studied clinical and socio-demographic correlates of health status in both conditions.
METHODS: We conducted a cross-sectional observational study in four outpatient clinics in the Southern part of The Netherlands, with subjects consisting of ambulatory (346 PAD and 188 CHF) patients. All patients completed the Short-Form 12 to assess their physical and mental health status. Information about socio-demographic, clinical risk factors, and disease severity indices was obtained from patients' medical records. Propensity methodology was applied to enhance comparability between both medical conditions.
RESULTS: Type of medical condition explained differences in health status (F = 33.1, P < .0001, Effect Size = 0.27). Impaired physical health status was more often reported in PAD patients (48.4%) compared with CHF patients (17.4%, Odds Ratio [OR] = 4.4, 95% Confidence Interval [CI] 2.3-8.8, P < .0001); impaired mental health status was more noted in CHF patients (43.5% vs. 22.0%, OR = 1.7, 95% CI 1.2-2.6, P = .002). In PAD, younger age (P = .002), low education (P = .02), cardiac history (P = .02), diabetes mellitus (P = .03), and a lower ankle brachial index (P = .003) were associated with worse physical health status; younger age (P = .01) and living without partner (P = .01) were associated with lower mental health status scores. In CHF, patients with comorbid diabetes mellitus (P < .001) and females (P = .001) reported worse physical health, whereas no clinical or socio-demographics were associated with mental health status.
CONCLUSIONS: By contrasting PAD patients' health status with another chronic disabling condition, the impact of PAD on patients' physical health status became evident; whereas mental health status was more affected in CHF, patients with PAD reported a greater physical burden as compared with CHF patients. PAD patients who were younger, lower-educated, without a partner or had a cardiac history especially reported a higher disease burden. Clinicians need to be aware of these differences in order to develop tailor-made disease management programs for different groups of cardiovascular patients.

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Year:  2009        PMID: 19958988     DOI: 10.1016/j.jvs.2009.07.109

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  6 in total

Review 1.  Assessment of functional status and quality of life in claudication.

Authors:  Ryan J Mays; Ivan P Casserly; Wendy M Kohrt; P Michael Ho; William R Hiatt; Mark R Nehler; Judith G Regensteiner
Journal:  J Vasc Surg       Date:  2011-02-18       Impact factor: 4.268

Review 2.  Treatment decisions for patients with peripheral artery disease and symptoms of claudication: Development process and alpha testing of the SHOW-ME PAD decision aid.

Authors:  Kim G Smolderen; Christina Pacheco; Jeremy Provance; Nancy Stone; Christine Fuss; Carole Decker; Matthew Bunte; Qurat-Ul-Ain Jelani; David M Safley; Eric Secemsky; Karen R Sepucha; Erica S Spatz; Carlos Mena-Hurtado; John A Spertus
Journal:  Vasc Med       Date:  2021-02-25       Impact factor: 3.239

Review 3.  Femoral-popliteal peripheral artery disease: From symptom presentation to management and treatment controversies.

Authors:  Anna K Krawisz; Aishwarya Raja; Eric A Secemsky
Journal:  Prog Cardiovasc Dis       Date:  2021-02-13       Impact factor: 8.194

4.  Gender differences in health status and adverse outcomes among patients with peripheral arterial disease.

Authors:  Rachel P Dreyer; Moniek van Zitteren; John F Beltrame; Robert Fitridge; Johan Denollet; Patrick W Vriens; John A Spertus; Kim G Smolderen
Journal:  J Am Heart Assoc       Date:  2014-12-23       Impact factor: 5.501

5.  Two-year Outcome of Quality of Life and Health Status for the Elderly with Chronic Limb-threatening Ischemia.

Authors:  Chloé M L Peters; Paul Lodder; Jolanda de Vries; Stijn L Steunenberg; Eelco J Veen; Hans G W de Groot; Gwan H Ho; Lijckle van der Laan
Journal:  Clin Interv Aging       Date:  2020-12-22       Impact factor: 4.458

Review 6.  Impact of non-cardiovascular comorbidities on the quality of life of patients with chronic heart failure: a scoping review.

Authors:  Josep Comín-Colet; Teresa Martín Lorenzo; Almudena González-Domínguez; Juan Oliva; Silvia Jiménez Merino
Journal:  Health Qual Life Outcomes       Date:  2020-10-07       Impact factor: 3.186

  6 in total

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