Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The renewed potential for folate antagonists in contemporary cancer chemotherapy.

× No keyword cloud information.

23 in total

1. Maternal tea consumption during early pregnancy and the risk of spina bifida.

Authors: Mahsa M Yazdy; Sarah C Tinker; Allen A Mitchell; Laurie A Demmer; Martha M Werler
Journal: Birth Defects Res A Clin Mol Teratol Date: 2012-05-29

2. Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates.

Authors: Aleem Gangjee; Yibin Qiu; Wei Li; Roy L Kisliuk
Journal: J Med Chem Date: 2008-09-25 Impact factor: 7.446

3. Human glycinamide ribonucleotide transformylase: active site mutants as mechanistic probes.

Authors: Wanda Manieri; Molly E Moore; Matthew B Soellner; Pearl Tsang; Carol A Caperelli
Journal: Biochemistry Date: 2007-01-09 Impact factor: 3.162

4. Synthesis and biological activity of substituted 2,4-diaminopyrimidines that inhibit Bacillus anthracis.

Authors: Baskar Nammalwar; Richard A Bunce; K Darrell Berlin; Christina R Bourne; Philip C Bourne; Esther W Barrow; William W Barrow
Journal: Eur J Med Chem Date: 2012-05-22 Impact factor: 6.514

5. Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidine as antifolates.

Authors: Aleem Gangjee; Jie Yang; John J McGuire; Roy L Kisliuk
Journal: Bioorg Med Chem Date: 2006-09-20 Impact factor: 3.641

6. Synthesis of classical, four-carbon bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

Authors: Aleem Gangjee; Yibin Zeng; John J McGuire; Roy L Kisliuk
Journal: J Med Chem Date: 2005-08-11 Impact factor: 7.446

7. 2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors.

Authors: Aleem Gangjee; Hiteshkumar D Jain; Jaclyn Phan; Xin Guo; Sherry F Queener; Roy L Kisliuk
Journal: Bioorg Med Chem Date: 2009-12-26 Impact factor: 3.641

8. Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.

Authors: A Rosowsky; J B Hynes; S F Queener
Journal: Antimicrob Agents Chemother Date: 1995-01 Impact factor: 5.191

9. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.

Authors: Aleem Gangjee; Wei Li; Roy L Kisliuk; Vivian Cody; Jim Pace; Jennifer Piraino; Jennifer Makin
Journal: J Med Chem Date: 2009-08-13 Impact factor: 7.446

10. Molecular docking studies on DMDP derivatives as human DHFR inhibitors.

Authors: Vivek Srivastava; Ashutosh Kumar; Bhartendu Nath Mishra; Mohammad Imran Siddiqi
Journal: Bioinformation Date: 2008-12-06