Literature DB >> 19958161

Therapeutic options for postmenopausal female sexual dysfunction.

F Al-Azzawi1, J Bitzer, U Brandenburg, C Castelo-Branco, A Graziottin, P Kenemans, M Lachowsky, S Mimoun, R E Nappi, S Palacios, A Schwenkhagen, J Studd, K Wylie, H-P Zahradnik.   

Abstract

BACKGROUND: Female sexual dysfunction (FSD) is a multidimensional problem combining biological, psychological and interpersonal elements of multiple etiologies. Menopause-related sexual dysfunction may not be reversible without therapy. Hormonal deficiency does not usually decrease in severity over time. Many options are available for the successful treatment of postmenopausal FSD.
OBJECTIVE: To review the pharmacological and non-pharmacological therapies available for postmenopausal FSD, focusing on practical recommendations for managing postmenopausal women with sexual complaints, through a literature review of the most relevant publications in this field. PSYCHOSOCIAL THERAPY: This type of therapy (basic counselling, physiotherapy and psychosexual intervention) is considered an adaptable step-by-step approach for diagnostic and therapeutic strategies, normally combined with biomedical interventions to provide optimal outcomes. PHARMACOLOGICAL THERAPY: For postmenopausal FSD, many interventional options are now available, including hormonal therapies such as estrogens, testosterone, combined estrogen/testosterone, tibolone and dehydroepiandrosterone.
CONCLUSIONS: Menopause and its transition represent significant risk factors for the development of sexual dysfunction. FSD impacts greatly on a patient's quality of life. Consequently, it is receiving more attention thanks to the development of effective treatments. Non-pharmacological approaches should be used first, focusing on lifestyle and psychosexual therapy. If required, proven effective hormonal and non-hormonal therapeutic options are available.

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Year:  2010        PMID: 19958161     DOI: 10.3109/13697130903437615

Source DB:  PubMed          Journal:  Climacteric        ISSN: 1369-7137            Impact factor:   3.005


  8 in total

Review 1.  Menopause and Sexuality.

Authors:  Kimberley Thornton; Judi Chervenak; Genevieve Neal-Perry
Journal:  Endocrinol Metab Clin North Am       Date:  2015-09       Impact factor: 4.741

2.  Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS).

Authors:  Hugh S Taylor; Aya Tal; Lubna Pal; Fangyong Li; Dennis M Black; Eliot A Brinton; Matthew J Budoff; Marcelle I Cedars; Wei Du; Howard N Hodis; Rogerio A Lobo; JoAnn E Manson; George R Merriam; Virginia M Miller; Frederick Naftolin; Genevieve Neal-Perry; Nanette F Santoro; Sherman M Harman
Journal:  JAMA Intern Med       Date:  2017-10-01       Impact factor: 21.873

3.  Comprehensive self-management reduces the negative impact of irritable bowel syndrome symptoms on sexual functioning.

Authors:  Margaret D Eugenio; Sang-Eun Jun; Kevin C Cain; Monica E Jarrett; Margaret M Heitkemper
Journal:  Dig Dis Sci       Date:  2012-06       Impact factor: 3.199

4.  The effect of education on sexual health of women with hypoactive sexual desire disorder: a randomized controlled trial.

Authors:  Maasumeh Kaviani; Tahereh Rahnavard; Sara Azima; Masoumeh Emamghoreishi; Nasrin Asadi; Mehrab Sayadi
Journal:  Int J Community Based Nurs Midwifery       Date:  2014-04

5.  Status of female sexual dysfunction among postmenopausal women in Bangladesh.

Authors:  Mohammad Ashraful Amin; Nusrat-E Mozid; Sanjana Binte Ahmed; Shakila Sharmin; Imran Hossain Monju; Shirin Shahadat Jhumur; Wharesha Sarker; Koustuv Dalal; Mohammad Delwer Hossain Hawlader
Journal:  BMC Womens Health       Date:  2022-10-04       Impact factor: 2.742

6.  Characterizing sexual function in patients with generalized anxiety disorder: a pooled analysis of three vilazodone studies.

Authors:  Anita H Clayton; Suresh Durgam; Xiongwen Tang; Changzheng Chen; Adam Ruth; Carl Gommoll
Journal:  Neuropsychiatr Dis Treat       Date:  2016-06-21       Impact factor: 2.570

7.  Mindfulness, cognitive behavioural and behaviour-based therapy for natural and treatment-induced menopausal symptoms: a systematic review and meta-analysis.

Authors:  C M van Driel; A Stuursma; M J Schroevers; M J Mourits; G H de Bock
Journal:  BJOG       Date:  2018-03-15       Impact factor: 6.531

Review 8.  Addressing Vulvovaginal Atrophy (VVA)/Genitourinary Syndrome of Menopause (GSM) for Healthy Aging in Women.

Authors:  Rossella E Nappi; Ellis Martini; Laura Cucinella; Silvia Martella; Lara Tiranini; Alessandra Inzoli; Emanuela Brambilla; David Bosoni; Chiara Cassani; Barbara Gardella
Journal:  Front Endocrinol (Lausanne)       Date:  2019-08-21       Impact factor: 5.555

  8 in total

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