Literature DB >> 19956432

Integrin signaling aberrations in prostate cancer.

Hira Lal Goel1, Naved Alam, Isaac N S Johnson, Lucia R Languino.   

Abstract

Integrins are cell surface receptors for extracellular matrix proteins and play a key role in cell survival, proliferation, migration and gene expression. Integrin signaling has been shown to be deregulated in several types of cancer, including prostate cancer. This review is focused on integrin signaling pathways known to be deregulated in prostate cancer and known to promote prostate cancer progression.

Entities:  

Year:  2009        PMID： 19956432      PMCID： PMC2757165     

Source DB:  PubMed          Journal:  Am J Transl Res            Impact factor:   4.060


  83 in total

1.  Clinical states in prostate cancer: toward a dynamic model of disease progression.

Authors:  H I Scher; G Heller
Journal:  Urology       Date:  2000-03       Impact factor: 2.649

Review 2.  Integrin-regulated FAK-Src signaling in normal and cancer cells.

Authors:  Satyajit K Mitra; David D Schlaepfer
Journal:  Curr Opin Cell Biol       Date:  2006-08-17       Impact factor: 8.382

3.  Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling.

Authors:  M Sumitomo; R Shen; M Walburg; J Dai; Y Geng; D Navarro; G Boileau; C N Papandreou; F G Giancotti; B Knudsen; D M Nanus
Journal:  J Clin Invest       Date:  2000-12       Impact factor: 14.808

4.  AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells.

Authors:  M Sun; G Wang; J E Paciga; R I Feldman; Z Q Yuan; X L Ma; S A Shelley; R Jove; P N Tsichlis; S V Nicosia; J Q Cheng
Journal:  Am J Pathol       Date:  2001-08       Impact factor: 4.307

Review 5.  Ras signaling in prostate cancer progression.

Authors:  Michael J Weber; Daniel Gioeli
Journal:  J Cell Biochem       Date:  2004-01-01       Impact factor: 4.429

6.  Differential expression of alpha 6 and alpha 2 very late antigen integrins in the normal, hyperplastic, and neoplastic prostate: simultaneous demonstration of cell surface receptors and their extracellular ligands.

Authors:  H Bonkhoff; U Stein; K Remberger
Journal:  Hum Pathol       Date:  1993-03       Impact factor: 3.466

7.  Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

Authors:  M Colombel; F Symmans; S Gil; K M O'Toole; D Chopin; M Benson; C A Olsson; S Korsmeyer; R Buttyan
Journal:  Am J Pathol       Date:  1993-08       Impact factor: 4.307

8.  AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts.

Authors:  Jing Zhang; Serk In Park; Marlene C Artime; Justin M Summy; Ami N Shah; Joshua A Bomser; Andrea Dorfleutner; Daniel C Flynn; Gary E Gallick
Journal:  J Clin Invest       Date:  2007-10       Impact factor: 14.808

9.  Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma.

Authors:  R B Nagle; J D Knox; C Wolf; G T Bowden; A E Cress
Journal:  J Cell Biochem Suppl       Date:  1994

10.  p27(kip1) acts as a downstream effector of and is coexpressed with the beta1C integrin in prostatic adenocarcinoma.

Authors:  M Fornaro; G Tallini; D Q Zheng; W M Flanagan; M Manzotti; L R Languino
Journal:  J Clin Invest       Date:  1999-02       Impact factor: 14.808
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  24 in total

1.  Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.

Authors:  Hira Lal Goel; Jean M Underwood; Jeffrey A Nickerson; Chung-Cheng Hsieh; Lucia R Languino
Journal:  J Cell Physiol       Date:  2010-07       Impact factor: 6.384

2.  Snail negatively regulates cell adhesion to extracellular matrix and integrin expression via the MAPK pathway in prostate cancer cells.

Authors:  Corey L Neal; Danielle Mckeithen; Valerie A Odero-Marah
Journal:  Cell Adh Migr       Date:  2011-05-01       Impact factor: 3.405

Review 3.  The laminin binding integrin alpha6beta1 in prostate cancer perineural invasion.

Authors:  Isis C Sroka; Todd A Anderson; Kathy M McDaniel; Raymond B Nagle; Matthew B Gretzer; Anne E Cress
Journal:  J Cell Physiol       Date:  2010-08       Impact factor: 6.384

4.  Do the expressions of epithelial-mesenchymal transition proteins, periostin, integrin-α4 and fibronectin correlate with clinico-pathological features and prognosis of metastatic castration-resistant prostate cancer?

Authors:  Ece Konac; Ilker Kiliccioglu; Emrullah Sogutdelen; Asiye U Dikmen; Gulsah Albayrak; Cenk Y Bilen
Journal:  Exp Biol Med (Maywood)       Date:  2017-08-24

5.  Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3.

Authors:  Kirsten Sandvig; Alicia Llorente
Journal:  Mol Cell Proteomics       Date:  2012-03-28       Impact factor: 5.911

6.  CD133, Trop-2 and alpha2beta1 integrin surface receptors as markers of putative human prostate cancer stem cells.

Authors:  Marco Trerotola; Swati Rathore; Hira Lal Goel; Jing Li; Saverio Alberti; Mauro Piantelli; Dave Adams; Zhong Jiang; Lucia R Languino
Journal:  Am J Transl Res       Date:  2010-03-15       Impact factor: 4.060

7.  Integrin α3β1 regulates tumor cell responses to stromal cells and can function to suppress prostate cancer metastatic colonization.

Authors:  Afshin Varzavand; Justin M Drake; Robert U Svensson; Mary E Herndon; Bo Zhou; Michael D Henry; Christopher S Stipp
Journal:  Clin Exp Metastasis       Date:  2012-12-06       Impact factor: 5.150

8.  Aberrant BAF57 signaling facilitates prometastatic phenotypes.

Authors:  Sucharitha Balasubramaniam; Clay E S Comstock; Adam Ertel; Kwang Won Jeong; Michael R Stallcup; Sankar Addya; Peter A McCue; William F Ostrander; Michael A Augello; Karen E Knudsen
Journal:  Clin Cancer Res       Date:  2013-03-14       Impact factor: 12.531

9.  α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway.

Authors:  Afshin Varzavand; Will Hacker; Deqin Ma; Katherine Gibson-Corley; Maria Hawayek; Omar J Tayh; James A Brown; Michael D Henry; Christopher S Stipp
Journal:  Cancer Res       Date:  2016-09-28       Impact factor: 12.701

10.  Long-term Tumor Adaptation after Radiotherapy: Therapeutic Implications for Targeting Integrins in Prostate Cancer.

Authors:  Iris Eke; Adeola Y Makinde; Molykutty J Aryankalayil; Jessica L Reedy; Deborah E Citrin; Sunita Chopra; Mansoor M Ahmed; C Norman Coleman
Journal:  Mol Cancer Res       Date:  2018-07-24       Impact factor: 5.852
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