Literature DB >> 19954371

Intravitreal combination of triamcinolone acetonide and bevacizumab (Kenacort-Avastin) in diffuse diabetic macular edema.

Miltiadis K Tsilimbaris1, Vassilios Pandeleondidis, Theoni Panagiototglou, Vassiliki Arvanitaki, Sofia Fragiskou, Maria Eleftheriadou, Chrysanthi Tsika, Theokliti Papadaki.   

Abstract

PURPOSE: To evaluate the effect of intravitreal injection of the combination of Triamcinolone Acetonide and Bevacizumab in patients with diabetic macular edema.
MATERIALS AND METHODS: Twenty seven eyes of 17 patients with diabetic macular edema were treated with an intravitreal injection of triamcinolone acetonide (2 mg) combined with bevacizumab (1.25 mg).
RESULTS: During the 6 months follow-up period 24 eyes (89%) had to repeat the treatment according to the monthly follow-up examination.The mean visual acuity and the central macular thickness improved significantly (P<0.05) throughout the follow-up period.
CONCLUSION: Intravitreal combination of Triamcinolone Acetonide and Bevacizumab seems to be effective in improving visual acuity and macular edema in patients with diabetic maculopathy.

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Year:  2009        PMID: 19954371     DOI: 10.3109/08820530903389775

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN: 0882-0538            Impact factor:   1.975


  5 in total

1.  Prediction, by retinal location, of the onset of diabetic edema in patients with nonproliferative diabetic retinopathy.

Authors:  Wendy W Harrison; Marcus A Bearse; Marilyn E Schneck; Brian E Wolff; Nicholas P Jewell; Shirin Barez; Andrew B Mick; Bernard J Dolan; Anthony J Adams
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-08-29       Impact factor: 4.799

2.  Reduction in the frequency of intravitreal bevacizumab administrations achieved by posterior subtenon injection of triamcinolone acetonide in patients with diffuse diabetic macular edema.

Authors:  Masahiko Shimura; Kanako Yasuda; Teruumi Minezaki; Hidetaka Noma
Journal:  Jpn J Ophthalmol       Date:  2016-06-15       Impact factor: 2.447

3.  The effect of combined treatment of bevacizumab and triamcinolone for diabetic macular edema refractory to previous intravitreal mono-injections.

Authors:  Ümit Yolcu; Güngör Sobaci
Journal:  Int Ophthalmol       Date:  2014-11-26       Impact factor: 2.031

4.  Current concepts in intravitreal drug therapy for diabetic retinopathy.

Authors:  Anant Pai; Maha M El Shafei; Osman A Z Mohammed; Mustafa Al Hashimi
Journal:  Saudi J Ophthalmol       Date:  2010-06-30

Review 5.  Clinical biomarkers and molecular basis for optimized treatment of diabetic retinopathy: current status and future prospects.

Authors:  Rohit Saxena; Digvijay Singh; Ravi Saklani; Suresh Kumar Gupta
Journal:  Eye Brain       Date:  2016-02-19
  5 in total

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