Literature DB >> 19954201

Ambient temperature nitrogen-directed difluoroalkynylborane Carboni-Lindsey cycloaddition reactions.

Jérôme F Vivat1, Harry Adams, Joseph P A Harrity.   

Abstract

The in situ generation of alkynyldifluoroboranes in the presence of N-heterocycle substituted tetrazines provides a convenient and direct method for the synthesis of pyridazine difluoroboranes. The reactions proceed in 10 min under ambient conditions and provide the opportunity to assemble unsymmetrical products with complete regiocontrol.

Entities:  

Year:  2010        PMID： 19954201     DOI： 10.1021/ol902573x

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  A Mild and Regioselective Route to Fluoroalkyl Aromatic Compounds via Directed Cycloaddition Reactions.

Authors:  David L Cousins; Yee Hwee Lim; Joseph P A Harrity
Journal:  J Org Chem       Date:  2022-07-08       Impact factor: 4.198

2.  Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions.

Authors:  Zbigniew Zawada; Zijian Guo; Bruno L Oliveira; Claudio D Navo; He Li; Pedro M S D Cal; Francisco Corzana; Gonzalo Jiménez-Osés; Gonçalo J L Bernardes
Journal:  Bioconjug Chem       Date:  2021-07-15       Impact factor: 4.774

3.  Lewis base directed cycloaddition reactions of 2-pyrones and alkynylaluminum reagents.

Authors:  Damien F Crépin; Joseph P A Harrity
Journal:  Org Lett       Date:  2013-08-05       Impact factor: 6.005
  3 in total

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