Literature DB >> 19953614

Complications and functional outcomes following complex oropharyngeal reconstruction.

Mark E Zafereo1, Randal S Weber, Jan S Lewin, Diana B Roberts, Matthew M Hanasono.   

Abstract

BACKGROUND: We sought to evaluate postoperative complications and functional outcomes in patients who underwent oropharyngeal reconstruction after oncologic resection.
METHODS: The evaluation constituted a retrospective review of 65 patients who underwent microvascular free flap (85%) and/or pectoralis pedicled flap (18%) oropharyngeal reconstruction after composite resection for advanced oropharyngeal squamous cell carcinoma.
RESULTS: Perioperative mortality was 1.5%. Overall, 29 patients (45%) experienced surgical or medical complications; however, only 2 patients (3%) required operative intervention. The flap success rate was 100%. Eighty-six percent of patients were decannulated, 34% were able to meet all of their nutritional needs orally, and 69% attained >80% speech intelligibility. Preoperative swallowing impairment was associated with postoperative feeding tube dependence (p = .006).
CONCLUSIONS: Microvascular free flap and/or pectoralis pedicled flap reconstruction of extensive oropharyngeal defects is safe and reliable, even with advanced disease. Although most patients achieved decannulation and functional speech, almost two thirds remained at least partially feeding tube dependent. 2009 Wiley Periodicals, Inc. Head Neck, 2010.

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Year:  2010        PMID: 19953614     DOI: 10.1002/hed.21290

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  9 in total

Review 1.  Surgery Versus Radiotherapy for Early Oropharyngeal Tumors: a Never-Ending Debate.

Authors:  Yan Monnier; Christian Simon
Journal:  Curr Treat Options Oncol       Date:  2015-09

Review 2.  De-Escalation Strategies for Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma-Where Are We Now?

Authors:  Jennifer A Silver; Sena Turkdogan; Catherine F Roy; Thavakumar Subramaniam; Melissa Henry; Nader Sadeghi
Journal:  Curr Oncol       Date:  2022-05-18       Impact factor: 3.109

3.  Factors Affecting Postoperative Complications After Reconstructive Surgery in Oral Carcinoma Patients: A Prospective Study of 100 Patients.

Authors:  Prateek Vijay Jain; Bhavesh Bang; Kapila Manikantan; Tiash Sinha; Gautam Biswas; Pattatheyil Arun
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2018-03-19

4.  Comparison of Anterolateral Thigh and Radial Forearm Free Flaps in Head and Neck Reconstruction.

Authors:  Carlo M Oranges; Barbara Ling; Mathias Tremp; Reto Wettstein; Daniel F Kalbermatten; Dirk J Schaefer
Journal:  In Vivo       Date:  2018 Jul-Aug       Impact factor: 2.155

5.  Examining the relationship of immunotherapy and wound complications following flap reconstruction in patients with head and neck cancer.

Authors:  Ashley C Mays; Bharat Yarlagadda; Virginie Achim; Ryan Jackson; Patrik Pipkorn; Andrew T Huang; Karthik Rajasekaran; Shaum Sridharan; Andrew J Rosko; Ryan K Orosco; Andrew M Coughlin; Mark K Wax; Yelizaveta Shnayder; William C Spanos; Donald Gregory Farwell; Lee S McDaniel; Matthew M Hanasono
Journal:  Head Neck       Date:  2021-01-08       Impact factor: 3.147

6.  Modified Clavien-Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer.

Authors:  Wei-Ling Jan; Hung-Chi Chen; Chang-Cheng Chang; Hsin-Han Chen; Pin-Keng Shih; Tsung-Chun Huang
Journal:  J Clin Med       Date:  2020-11-22       Impact factor: 4.241

7.  Reconstruction of medium-size defects of the oral cavity: radial forearm free flap vs facial artery musculo-mucosal flap.

Authors:  Badr Ibrahim; Akram Rahal; Eric Bissada; Apostolos Christopoulos; Louis Guertin; Tareck Ayad
Journal:  J Otolaryngol Head Neck Surg       Date:  2021-12-03

Review 8.  Reconstructive Surgery for Head and Neck Cancer Patients.

Authors:  Matthew M Hanasono
Journal:  Adv Med       Date:  2014-11-09

Review 9.  Transoral robotic surgery for oropharyngeal cancer: patient selection and special considerations.

Authors:  R Michael Baskin; Brian J Boyce; Robert Amdur; William M Mendenhall; Kathryn Hitchcock; Natalie Silver; Peter T Dziegielewski
Journal:  Cancer Manag Res       Date:  2018-04-20       Impact factor: 3.989

  9 in total

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