Literature DB >> 19952650

Staged excision of lentigo maligna and lentigo maligna melanoma: a 10-year experience.

Mark W Bosbous1, William W Dzwierzynski, Marcelle Neuburg.   

Abstract

BACKGROUND: The treatment of lentigo maligna and lentigo maligna melanoma presents a difficult problem for clinicians. Published guidelines recommend a 5-mm excision margin for lentigo maligna and a 1-cm margin for lentigo maligna melanoma, yet these are often inadequate. The authors' purpose is to report their 10-year experience using staged excision for the treatment of lentigo maligna and lentigo maligna melanoma of the head and neck.
METHODS: Staged excision was performed on 59 patients over a 10-year period. Data on patient demographics, lesion characteristics, and treatment were collected through an institutional review board-approved chart review.
RESULTS: Using staged excision, 62.7 percent of patients required a 10-mm or greater margin to achieve clearance of tumor. Two or more stages of excision were required in 50.9 percent of patients. Invasive melanoma (lentigo maligna melanoma) was identified in 10.2 percent of patients initially diagnosed with lentigo maligna. There was one (1.7 percent) documented recurrence during a median 2.25-year follow-up period (range, 0 to 10.17 years).
CONCLUSIONS: Staged excision is an effective treatment for lentigo maligna and lentigo maligna melanoma. Previously published recommendations of 5-mm margins for wide local excision are inadequate for tumors located on the head and neck.

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Year:  2009        PMID: 19952650     DOI: 10.1097/PRS.0b013e3181bcf002

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  7 in total

Review 1.  Lentigo maligna and lentigo maligna melanoma: contemporary issues in diagnosis and management.

Authors:  Karen L Connolly; Kishwer S Nehal; Klaus J Busam
Journal:  Melanoma Manag       Date:  2015-05-18

2.  Staged Excision for Lentigo Maligna and Lentigo Maligna Melanoma: Analysis of Surgical Margins and Long-term Recurrence in 68 Cases from a Single Practice.

Authors:  Joshua B Wilson; Hobart W Walling; Richard K Scupham; Andrew K Bean; Roger I Ceilley; Kirsten E Goetz
Journal:  J Clin Aesthet Dermatol       Date:  2016-06-01

Review 3.  Diagnosis and management of lentigo maligna: a review.

Authors:  Julia M Kasprzak; Yaohui G Xu
Journal:  Drugs Context       Date:  2015-05-29

Review 4.  Reviewing Challenges in the Diagnosis and Treatment of Lentigo Maligna and Lentigo-Maligna Melanoma.

Authors:  Margit L W Juhász; Ellen S Marmur
Journal:  Rare Cancers Ther       Date:  2015-10-15

5.  Recurrence Rate of Melanoma in Situ when Treated with Serial Disk Staged Excision: A Case Series.

Authors:  Daniel Garcia; Robert E Eilers; S Brian Jiang
Journal:  J Clin Investig Dermatol       Date:  2017-02-27

Review 6.  Current perspectives on Mohs micrographic surgery for melanoma.

Authors:  Derek Beaulieu; Ramin Fathi; Divya Srivastava; Rajiv I Nijhawan
Journal:  Clin Cosmet Investig Dermatol       Date:  2018-06-20

7.  Handheld reflectance confocal microscopy: Personalized and accurate presurgical delineation of lentigo maligna (melanoma).

Authors:  Yannick S Elshot; Biljana Zupan-Kajcovski; William M C Klop; Marcel W Bekkenk; Marianne B Crijns; Menno A de Rie; Alfons J M Balm
Journal:  Head Neck       Date:  2020-11-24       Impact factor: 3.147

  7 in total

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