Literature DB >> 19952542

Illness during pregnancy and bacterial vaginosis are associated with in-utero HIV-1 transmission.

Carey Farquhar1, Dorothy Mbori-Ngacha, Julie Overbaugh, Dalton Wamalwa, Jennifer Harris, Rose Bosire, Grace John-Stewart.   

Abstract

HIV-1 transmission in utero accounts for 20-30% of vertical transmission events in breast-feeding populations. In a prospective study of 463 HIV-1-infected mothers and infants, illness during pregnancy was associated with 2.6-fold increased risk of in-utero HIV-1 transmission [95% confidence interval (CI) 1.2-5.8] and bacterial vaginosis with a three-fold increase (95% CI 1.0-7.0) after adjusting for maternal HIV-1 viral load. Interventions targeting these novel risk factors could lead to more effective prevention of transmission during pregnancy.

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Year:  2010        PMID: 19952542      PMCID: PMC2788745          DOI: 10.1097/QAD.0b013e32832326d8

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  7 in total

1.  A phase III clinical trial of antibiotics to reduce chorioamnionitis-related perinatal HIV-1 transmission.

Authors:  Taha E Taha; Elizabeth R Brown; Irving F Hoffman; Wafaie Fawzi; Jennifer S Read; Moses Sinkala; Francis E A Martinson; George Kafulafula; Gernard Msamanga; Lynda Emel; Samuel Adeniyi-Jones; Robert Goldenberg
Journal:  AIDS       Date:  2006-06-12       Impact factor: 4.177

2.  Herpes simplex virus type 2 and risk of intrapartum human immunodeficiency virus transmission.

Authors:  Alison L Drake; Grace C John-Stewart; Anna Wald; Dorothy A Mbori-Ngacha; Rose Bosire; Dalton C Wamalwa; Barbara L Lohman-Payne; Rhoda Ashley-Morrow; Lawrence Corey; Carey Farquhar
Journal:  Obstet Gynecol       Date:  2007-02       Impact factor: 7.661

3.  Acute and chronic chorioamnionitis and the risk of perinatal human immunodeficiency virus-1 transmission.

Authors:  Benjamin H Chi; Victor Mudenda; Jens Levy; Moses Sinkala; Robert L Goldenberg; Jeffrey S A Stringer
Journal:  Am J Obstet Gynecol       Date:  2006-01       Impact factor: 8.661

Review 4.  Reducing the risk of mother-to-child human immunodeficiency virus transmission: past successes, current progress and challenges, and future directions.

Authors:  Mary Glenn Fowler; Margaret A Lampe; Denise J Jamieson; Athena P Kourtis; Martha F Rogers
Journal:  Am J Obstet Gynecol       Date:  2007-09       Impact factor: 8.661

5.  Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission.

Authors:  Newton I Kumwenda; Donald R Hoover; Lynne M Mofenson; Michael C Thigpen; George Kafulafula; Qing Li; Linda Mipando; Kondwani Nkanaunena; Tsedal Mebrahtu; Marc Bulterys; Mary Glenn Fowler; Taha E Taha
Journal:  N Engl J Med       Date:  2008-06-04       Impact factor: 91.245

6.  Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomised controlled trials.

Authors:  Abubaker Bedri; Berhanu Gudetta; Abdulhamid Isehak; Solomon Kumbi; Sileshi Lulseged; Yohannes Mengistu; Arvind V Bhore; Ramesh Bhosale; Venkat Varadhrajan; Nikhil Gupte; Jayagowri Sastry; Nishi Suryavanshi; Srikanth Tripathy; Francis Mmiro; Michael Mubiru; Carolyne Onyango; Adrian Taylor; Philippa Musoke; Clemensia Nakabiito; Aida Abashawl; Rahel Adamu; Gretchen Antelman; Robert C Bollinger; Patricia Bright; Mohammad A Chaudhary; Jacqueline Coberly; Laura Guay; Mary Glenn Fowler; Amita Gupta; Elham Hassen; J Brooks Jackson; Lawrence H Moulton; Uma Nayak; Saad B Omer; Lidia Propper; Malathi Ram; Vivian Rexroad; Andrea J Ruff; Anita Shankar; Sheryl Zwerski
Journal:  Lancet       Date:  2008-07-26       Impact factor: 79.321

Review 7.  Biological mechanisms of vertical human immunodeficiency virus (HIV-1) transmission.

Authors:  Dara A Lehman; Carey Farquhar
Journal:  Rev Med Virol       Date:  2007 Nov-Dec       Impact factor: 6.989

  7 in total
  15 in total

1.  Immune-based approaches to the prevention of mother-to-child transmission of HIV-1: active and passive immunization.

Authors:  Barb Lohman-Payne; Jennifer Slyker; Sarah L Rowland-Jones
Journal:  Clin Perinatol       Date:  2010-12       Impact factor: 3.430

2.  Examining targets for HIV prevention: intravaginal practices in Urban Lusaka, Zambia.

Authors:  Maria L Alcaide; Maureen Chisembele; Miriam Mumbi; Emeria Malupande; Deborah Jones
Journal:  AIDS Patient Care STDS       Date:  2014-02-25       Impact factor: 5.078

3.  Vaginal cleansing practices in HIV infected Zambian women.

Authors:  Maria L Alcaide; Miriam Mumbi; Ndashi Chitalu; Deborah Jones
Journal:  AIDS Behav       Date:  2013-03

4.  The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIV.

Authors:  Leigh F Johnson; Kathryn Stinson; Marie-Louise Newell; Ruth M Bland; Harry Moultrie; Mary-Ann Davies; Thomas M Rehle; Rob E Dorrington; Gayle G Sherman
Journal:  J Acquir Immune Defic Syndr       Date:  2012-04-01       Impact factor: 3.731

5.  Different regions of HIV-1 subtype C env are associated with placental localization and in utero mother-to-child transmission.

Authors:  Surender B Kumar; Samuel K Handelman; Igor Voronkin; Victor Mwapasa; Daniel Janies; Stephen J Rogerson; Steven R Meshnick; Jesse J Kwiek
Journal:  J Virol       Date:  2011-05-04       Impact factor: 5.103

6.  Prevalence of bacterial vaginosis and aerobic vaginitis and their associated risk factors among pregnant women from northern Ethiopia: A cross-sectional study.

Authors:  Gebrehiwet Tesfay Yalew; Saravanan Muthupandian; Kiflom Hagos; Letemichael Negash; Gopinath Venkatraman; Yemane Mengsteab Hagos; Hadush Negash Meles; Hagos Haileslasie Weldehaweriat; Hussein O M Al-Dahmoshi; Morteza Saki
Journal:  PLoS One       Date:  2022-02-25       Impact factor: 3.240

7.  Deep sequencing of the vaginal microbiota of women with HIV.

Authors:  Ruben Hummelen; Andrew D Fernandes; Jean M Macklaim; Russell J Dickson; John Changalucha; Gregory B Gloor; Gregor Reid
Journal:  PLoS One       Date:  2010-08-12       Impact factor: 3.240

8.  An intervention to decrease intravaginal practices in hiv-infected women in Zambia: a pilot study.

Authors:  Maria L Alcaide; Miriam Mumbi; Ndashi Chitalu; Deborah L Jones
Journal:  J Assoc Nurses AIDS Care       Date:  2013-01-20       Impact factor: 1.354

9.  Mycoplasma genitalium infection among HIV-infected pregnant African women and implications for mother-to-child transmission of HIV.

Authors:  Alison C Roxby; Krista Yuhas; Carey Farquhar; Rose Bosire; Dorothy Mbori-Ngacha; Barbra A Richardson; Patricia A Totten; Grace John-Stewart
Journal:  AIDS       Date:  2019-11-15       Impact factor: 4.177

Review 10.  The role of co-infections in mother-to-child transmission of HIV.

Authors:  Caroline C King; Sascha R Ellington; Athena P Kourtis
Journal:  Curr HIV Res       Date:  2013-01       Impact factor: 1.581

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