AIM: To describe the incidence of acute renal insufficiency after dipyrone overdose in children. METHODS: The medical records of all patients < or =18 years of age during a 3-year period presenting at Assaf Harofeh Medical Center due to toxic exposure were retrospectively reviewed. Patients suffering from dipyrone overdose were compared with all the other patients. RESULTS: 235 cases were included in the final analysis. Of these, 26 (11%) patients were exposed to dipyrone (median age 15 years). Three of the 26 patients (12%) had transient non-oliguric renal insufficiency. One other patient who did not receive dipyrone also developed transient renal insufficiency. CONCLUSIONS: Dipyrone overdose is frequent and may cause acute non-oliguric renal insufficiency. Renal function should be monitored in such patients.
AIM: To describe the incidence of acute renal insufficiency after dipyroneoverdose in children. METHODS: The medical records of all patients < or =18 years of age during a 3-year period presenting at Assaf Harofeh Medical Center due to toxic exposure were retrospectively reviewed. Patients suffering from dipyroneoverdose were compared with all the other patients. RESULTS: 235 cases were included in the final analysis. Of these, 26 (11%) patients were exposed to dipyrone (median age 15 years). Three of the 26 patients (12%) had transient non-oliguric renal insufficiency. One other patient who did not receive dipyrone also developed transient renal insufficiency. CONCLUSIONS:Dipyroneoverdose is frequent and may cause acute non-oliguric renal insufficiency. Renal function should be monitored in such patients.
Authors: Z Bárzaga Arencibia; A López Leyva; Y Mejías Peña; A R González Reyes; E Fernández Manzano; I Choonara Journal: Eur J Clin Pharmacol Date: 2012-02-08 Impact factor: 2.953
Authors: Amin Polzin; Lisa Dannenberg; Carolin Helten; Martin Pöhl; Daniel Metzen; Philipp Mourikis; Christof Dücker; Ursula Marschall; Helmut L'Hoest; Beata Hennig; Saif Zako; Kajetan Trojovsky; Tobias Petzold; Christian Jung; Bodo Levkau; Tobias Zeus; Karsten Schrör; Thomas Hohlfeld; Malte Kelm Journal: J Am Heart Assoc Date: 2021-11-02 Impact factor: 5.501