| Literature DB >> 1995186 |
J E Paulsen1, K Sundby-Hall, L Endresen, H E Rugstad, K L Reichelt, K Elgjo.
Abstract
The peptide pyroGlu-Gln-Gly-Ser-Asn, recently isolated from mouse liver, inhibited DNA synthesis and proliferation in vitro of MH1C1 cells, a rat clonal strain derived from a Morris transplantable hepatoma. Both the biological peptide isolated from mouse liver and the synthetic homolog showed bell-shaped dose-response curves. Maximal inhibition (approximately 50%) was observed at two separate dose ranges: one at 10(-7)-10(-10) M, and one at 10(-14)-10(-15) M.Entities:
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Year: 1991 PMID： 1995186 DOI： 10.1093/carcin/12.2.207
Source DB: PubMed Journal: Carcinogenesis ISSN： 0143-3334 Impact factor: 4.944