BACKGROUND: Previous studies have reported varying levels of resistance against imidacloprid in several insect species, including populations of the peach-potato aphid, Myzus persicae (Sulzer). These cases of resistance have been attributed to either target-site resistance or enhanced detoxification. In this study, a clone of M. persicae originating from Greece revealed a 60-fold resistance factor to imidacloprid. RESULTS: The Greek clone is compared in terms of metabolic enzyme activity and synergism profiles with other M. persicae clones showing lower imidacloprid resistance. CONCLUSION: A combination of in vitro biochemical assays and in vivo differential synergism studies using PBO and a close analogue EN 16/5-1 suggests that the mechanism conferring increased resistance in this clone is primarily due to enhanced oxidase activity.
BACKGROUND: Previous studies have reported varying levels of resistance against imidacloprid in several insect species, including populations of the peach-potato aphid, Myzus persicae (Sulzer). These cases of resistance have been attributed to either target-site resistance or enhanced detoxification. In this study, a clone of M. persicae originating from Greece revealed a 60-fold resistance factor to imidacloprid. RESULTS: The Greek clone is compared in terms of metabolic enzyme activity and synergism profiles with other M. persicae clones showing lower imidacloprid resistance. CONCLUSION: A combination of in vitro biochemical assays and in vivo differential synergism studies using PBO and a close analogue EN 16/5-1 suggests that the mechanism conferring increased resistance in this clone is primarily due to enhanced oxidase activity.
Authors: Alin M Puinean; Stephen P Foster; Linda Oliphant; Ian Denholm; Linda M Field; Neil S Millar; Martin S Williamson; Chris Bass Journal: PLoS Genet Date: 2010-06-24 Impact factor: 5.917
Authors: Chris Bass; Alin M Puinean; Melanie Andrews; Penny Cutler; Miriam Daniels; Jan Elias; Verity Laura Paul; Andrew J Crossthwaite; Ian Denholm; Linda M Field; Stephen P Foster; Rob Lind; Martin S Williamson; Russell Slater Journal: BMC Neurosci Date: 2011-05-31 Impact factor: 3.288