BACKGROUND/AIMS: Dieulafoy lesions are an important cause of upper gastrointestinal bleeding. The purpose of this study was to assess the efficacy of endoscopic treatment for these lesions and to identify the possible predictive factors for rebleeding associated with clinical and endoscopic characteristics. METHODS: Records from 44 patients admitted with Dieulafoy bleeding between January 2006 and December 2007 were reviewed. We retrospectively analyzed the clinical and endoscopic findings and then correlated the rebleeding risk factors with Dieulafoy lesions. RESULTS: Primary hemostasis was achieved by endoscopic treatment in 39 patients (88.6%). There were no significant differences between the rebleeding and non-rebleeding groups with respect to age, gender, initial hemoglobin levels, presence of shock, concurrent disease, location of bleeding, or initial hemostatic treatment methods. However, the use of non-steroidal anti-inflammatory drugs or anticoagulants (p=0.02) and active stages in the Forrest classification (p<0.01) were risk factors for rebleeding after endoscopic therapy. CONCLUSIONS: Endoscopic therapy is effective and safe for treating Dieulafoy lesions, and it has both short- and long-term benefits. Early identification of risk factors such as the use of non-steroidal anti-inflammatory drugs or anticoagulants and the Forrest classification of bleeding predict the outcome of Dieulafoy lesions.
BACKGROUND/AIMS: Dieulafoy lesions are an important cause of upper gastrointestinal bleeding. The purpose of this study was to assess the efficacy of endoscopic treatment for these lesions and to identify the possible predictive factors for rebleeding associated with clinical and endoscopic characteristics. METHODS: Records from 44 patients admitted with Dieulafoy bleeding between January 2006 and December 2007 were reviewed. We retrospectively analyzed the clinical and endoscopic findings and then correlated the rebleeding risk factors with Dieulafoy lesions. RESULTS: Primary hemostasis was achieved by endoscopic treatment in 39 patients (88.6%). There were no significant differences between the rebleeding and non-rebleeding groups with respect to age, gender, initial hemoglobin levels, presence of shock, concurrent disease, location of bleeding, or initial hemostatic treatment methods. However, the use of non-steroidal anti-inflammatory drugs or anticoagulants (p=0.02) and active stages in the Forrest classification (p<0.01) were risk factors for rebleeding after endoscopic therapy. CONCLUSIONS: Endoscopic therapy is effective and safe for treating Dieulafoy lesions, and it has both short- and long-term benefits. Early identification of risk factors such as the use of non-steroidal anti-inflammatory drugs or anticoagulants and the Forrest classification of bleeding predict the outcome of Dieulafoy lesions.
Authors: Federico Iacopini; Lucio Petruzziello; Michele Marchese; Alberto Larghi; Cristiano Spada; Pietro Familiari; Andrea Tringali; Maria Elena Riccioni; Armando Gabbrielli; Guido Costamagna Journal: Gastrointest Endosc Date: 2007-07 Impact factor: 9.427
Authors: S Asaki; H Sato; T Nishimura; S Ohkubo; R Yamagata; S Ito; Y Saito; S Miyazaki; N Yaginuma Journal: Tohoku J Exp Med Date: 1988-02 Impact factor: 1.848
Authors: Yoo Jin Lee; Eun Soo Kim; Yu Jin Hah; Kyung Sik Park; Kwang Bum Cho; Byoung Kuk Jang; Woo Jin Chung; Jae Seok Hwang Journal: J Korean Med Sci Date: 2013-09-25 Impact factor: 2.153
Authors: Dong-Won Ahn; Young Soo Park; Sang Hyub Lee; Cheol Min Shin; Jin-Hyeok Hwang; Jin-Wook Kim; Sook-Hyang Jeong; Nayoung Kim; Dong Ho Lee Journal: Korean J Intern Med Date: 2016-04-06 Impact factor: 2.884