Literature DB >> 19949394

Deal watch: Alcon licenses complement pathway inhibitor for macular degeneration.

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Year:  2009        PMID： 19949394     DOI： 10.1038/nrd3063

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  6 in total

Review 1.  Complement inhibitors for age-related macular degeneration.

Authors:  Michael A Williams; Gareth J McKay; Usha Chakravarthy
Journal:  Cochrane Database Syst Rev       Date:  2014-01-15

2.  Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency.

Authors:  Hongchang Qu; Paola Magotti; Daniel Ricklin; Emilia L Wu; Ioannis Kourtzelis; You-Qiang Wu; Yiannis N Kaznessis; John D Lambris
Journal:  Mol Immunol       Date:  2010-11-09       Impact factor: 4.407

3.  Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin.

Authors:  Patrick J Knerr; Apostolia Tzekou; Daniel Ricklin; Hongchang Qu; Hui Chen; Wilfred A van der Donk; John D Lambris
Journal:  ACS Chem Biol       Date:  2011-05-23       Impact factor: 5.100

4.  New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties.

Authors:  Hongchang Qu; Daniel Ricklin; Hongjun Bai; Hui Chen; Edimara S Reis; Mateusz Maciejewski; Apostolia Tzekou; Robert A DeAngelis; Ranillo R G Resuello; Florea Lupu; Paul N Barlow; John D Lambris
Journal:  Immunobiology       Date:  2012-06-17       Impact factor: 3.144

5.  Age-related macular degeneration.

Authors:  Giuseppe Querques; Fernando Onofrio Avellis; Lea Querques; Francesco Bandello; Eric H Souied
Journal:  Clin Ophthalmol       Date:  2011-05-18

6.  Computational analysis of complement inhibitor compstatin using molecular dynamics.

Authors:  Didier Devaurs; Dinler A Antunes; Lydia E Kavraki
Journal:  J Mol Model       Date:  2020-08-12       Impact factor: 1.810
  6 in total

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