Literature DB >> 19949311

N-acetylcysteine, reactive oxygen species and beyond.

Shi-Yong Sun1.   

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Year:  2010        PMID: 19949311      PMCID: PMC2854288          DOI: 10.4161/cbt.9.2.10583

Source DB:  PubMed          Journal:  Cancer Biol Ther        ISSN: 1538-4047            Impact factor:   4.742


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  18 in total

1.  Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells.

Authors:  Wei Zou; Ping Yue; Na Lin; Min He; Zhongmei Zhou; Sagal Lonial; Fadlo R Khuri; Binghe Wang; Shi-Yong Sun
Journal:  Clin Cancer Res       Date:  2006-01-01       Impact factor: 12.531

Review 2.  N-acetylcysteine: pharmacological considerations and experimental and clinical applications.

Authors:  I A Cotgreave
Journal:  Adv Pharmacol       Date:  1997

3.  N-acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity.

Authors:  K Y Kim; T Rhim; I Choi; S S Kim
Journal:  J Biol Chem       Date:  2001-08-16       Impact factor: 5.157

4.  Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells.

Authors:  Andrew Fribley; Qinghua Zeng; Cun-Yu Wang
Journal:  Mol Cell Biol       Date:  2004-11       Impact factor: 4.272

Review 5.  Molecular mechanisms of N-acetylcysteine actions.

Authors:  M Zafarullah; W Q Li; J Sylvester; M Ahmad
Journal:  Cell Mol Life Sci       Date:  2003-01       Impact factor: 9.261

6.  Downregulation of c-FLIP, XIAP and Mcl-1 protein as well as depletion of reduced glutathione contribute to the apoptosis induction of glycyrrhetinic acid derivatives in leukemia cells.

Authors:  Dandan Song; Yuan Gao; Rui Wang; Dan Liu; Linxiang Zhao; Yongkui Jing
Journal:  Cancer Biol Ther       Date:  2010-01-09       Impact factor: 4.742

7.  The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance.

Authors:  Takashi Ikeda; Michael Sporn; Tadashi Honda; Gordon W Gribble; Donald Kufe
Journal:  Cancer Res       Date:  2003-09-01       Impact factor: 12.701

8.  Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.

Authors:  Takashi Ikeda; Yukiko Nakata; Fumihiko Kimura; Ken Sato; Kenneth Anderson; Kazuo Motoyoshi; Michael Sporn; Donald Kufe
Journal:  Mol Cancer Ther       Date:  2004-01       Impact factor: 6.261

9.  Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells.

Authors:  Yi-He Ling; Leonard Liebes; Yiyu Zou; Roman Perez-Soler
Journal:  J Biol Chem       Date:  2003-06-23       Impact factor: 5.157

10.  Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors.

Authors:  Encouse B Golden; Philip Y Lam; Adel Kardosh; Kevin J Gaffney; Enrique Cadenas; Stan G Louie; Nicos A Petasis; Thomas C Chen; Axel H Schönthal
Journal:  Blood       Date:  2009-02-03       Impact factor: 22.113

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  84 in total

1.  The cathepsin B inhibitor z-FA-CMK induces cell death in leukemic T cells via oxidative stress.

Authors:  K Y Liow; Sek C Chow
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2017-10-31       Impact factor: 3.000

2.  An anti-ASCT2 monoclonal antibody suppresses gastric cancer growth by inducing oxidative stress and antibody dependent cellular toxicity in preclinical models.

Authors:  Aya Osanai-Sasakawa; Kenta Hosomi; Yoshiki Sumitomo; Takuya Takizawa; Shiho Tomura-Suruki; Minami Imaizumi; Noriyuki Kasai; Tze Wei Poh; Kazuya Yamano; Wei Peng Yong; Koji Kono; Satoshi Nakamura; Toshihiko Ishii; Ryuichiro Nakai
Journal:  Am J Cancer Res       Date:  2018-08-01       Impact factor: 6.166

3.  Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.

Authors:  Elyse A Schmidt; Brian E Fee; Stanley C Henry; Amanda G Nichols; Mari L Shinohara; Jeffrey C Rathmell; Nancie J MacIver; Jörn Coers; Olga R Ilkayeva; Timothy R Koves; Gregory A Taylor
Journal:  J Biol Chem       Date:  2017-02-01       Impact factor: 5.157

4.  Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.

Authors:  Nilanjana Chatterjee; Evangelos Pazarentzos; Manasi K Mayekar; Philippe Gui; David V Allegakoen; Gorjan Hrustanovic; Victor Olivas; Luping Lin; Erik Verschueren; Jeffrey R Johnson; Matan Hofree; Jenny J Yan; Billy W Newton; John V Dollen; Charles H Earnshaw; Jennifer Flanagan; Elton Chan; Saurabh Asthana; Trey Ideker; Wei Wu; Junji Suzuki; Benjamin A Barad; Yuriy Kirichok; James S Fraser; William A Weiss; Nevan J Krogan; Asmin Tulpule; Amit J Sabnis; Trever G Bivona
Journal:  Cell Rep       Date:  2019-08-27       Impact factor: 9.423

5.  Gestational hypoxia increases reactive oxygen species and inhibits steroid hormone-mediated upregulation of Ca(2+)-activated K(+) channel function in uterine arteries.

Authors:  Ronghui Zhu; Xiaohui Huang; Xiang-Qun Hu; DaLiao Xiao; Lubo Zhang
Journal:  Hypertension       Date:  2014-05-27       Impact factor: 10.190

6.  Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy.

Authors:  Taiga Miyajima; Geetha Melangath; Shan Zhu; Neha Deshpande; Shivakumar Vasanth; Bodhisattwa Mondal; Varun Kumar; Yuming Chen; Marianne O Price; Francis W Price; Eleanor G Rogan; Muhammad Zahid; Ula V Jurkunas
Journal:  Free Radic Biol Med       Date:  2019-12-17       Impact factor: 7.376

7.  Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected.

Authors:  Cailing Liu; Taiga Miyajima; Geetha Melangath; Takashi Miyai; Shivakumar Vasanth; Neha Deshpande; Varun Kumar; Stephan Ong Tone; Reena Gupta; Shan Zhu; Dijana Vojnovic; Yuming Chen; Eleanor G Rogan; Bodhiswatta Mondal; Muhammad Zahid; Ula V Jurkunas
Journal:  Proc Natl Acad Sci U S A       Date:  2019-12-18       Impact factor: 11.205

8.  Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

Authors:  Alberto Pauletti; Gaetano Terrone; Tawfeeq Shekh-Ahmad; Alessia Salamone; Teresa Ravizza; Massimo Rizzi; Anna Pastore; Rosaria Pascente; Li-Ping Liang; Bianca R Villa; Silvia Balosso; Andrey Y Abramov; Erwin A van Vliet; Ennio Del Giudice; Eleonora Aronica; Manisha Patel; Matthew C Walker; Annamaria Vezzani
Journal:  Brain       Date:  2019-07-01       Impact factor: 13.501

9.  Direct effect of chronic hypoxia in suppressing large conductance Ca(2+)-activated K(+) channel activity in ovine uterine arteries via increasing oxidative stress.

Authors:  Xiang-Qun Hu; Xiaohui Huang; Daliao Xiao; Lubo Zhang
Journal:  J Physiol       Date:  2015-12-21       Impact factor: 5.182

10.  ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors.

Authors:  Marianna Halasi; Ming Wang; Tanmay S Chavan; Vadim Gaponenko; Nissim Hay; Andrei L Gartel
Journal:  Biochem J       Date:  2013-09-01       Impact factor: 3.857

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