D L Belavý1, T Miokovic, G Armbrecht, J Rittweger, D Felsenberg. 1. Center for Muscle and Bone Research, Charité Campus Benjamin Franklin, Free University and Humboldt-University Berlin, Berlin, Germany. belavy@gmail.com
Abstract
OBJECTIVES: The current study aimed to examine the effectiveness of a resistive vibration exercise countermeasure during prolonged bed-rest in preventing lower-limb muscle atrophy. METHODS: 20 male subjects underwent 56-days of bed-rest and were assigned to either an inactive control, or a countermeasure group which performed high-load resistive exercises (including squats, heel raises and toe raises) with whole-body vibration. Magnetic resonance imaging of the lower-limbs was performed at two-weekly intervals. Volume of individual muscles was calculated. RESULTS: Countermeasure exercise reduced atrophy in the triceps surae and the vastii muscles (F>3.0, p<.025). Atrophy of the peroneals, tibialis posterior and toe flexors was less in the countermeasure-subjects, though statistical evidence for this was weak (F<or=2.3, p>or=.071). Atrophy in the hamstring muscles was similar in both groups (F<1.1, p>.38). The adductor longus, sartiorius and rectus femoris muscles showed little loss of muscle volume during bed-rest (F<1.7, p>.15). CONCLUSIONS: The countermeasure exercise programme was effective in reducing atrophy in the extensors of the knee and ankle but not the hamstrings.
OBJECTIVES: The current study aimed to examine the effectiveness of a resistive vibration exercise countermeasure during prolonged bed-rest in preventing lower-limb muscle atrophy. METHODS: 20 male subjects underwent 56-days of bed-rest and were assigned to either an inactive control, or a countermeasure group which performed high-load resistive exercises (including squats, heel raises and toe raises) with whole-body vibration. Magnetic resonance imaging of the lower-limbs was performed at two-weekly intervals. Volume of individual muscles was calculated. RESULTS: Countermeasure exercise reduced atrophy in the triceps surae and the vastii muscles (F>3.0, p<.025). Atrophy of the peroneals, tibialis posterior and toe flexors was less in the countermeasure-subjects, though statistical evidence for this was weak (F<or=2.3, p>or=.071). Atrophy in the hamstring muscles was similar in both groups (F<1.1, p>.38). The adductor longus, sartiorius and rectus femoris muscles showed little loss of muscle volume during bed-rest (F<1.7, p>.15). CONCLUSIONS: The countermeasure exercise programme was effective in reducing atrophy in the extensors of the knee and ankle but not the hamstrings.
Authors: D L Belavý; G Beller; G Armbrecht; F H Perschel; R Fitzner; O Bock; H Börst; C Degner; U Gast; D Felsenberg Journal: Osteoporos Int Date: 2010-09-03 Impact factor: 4.507