| Literature DB >> 19947623 |
Pradeep K Singh1, Vinod K Singh.
Abstract
A highly enantioselective Friedel-Crafts alkylation of pyrroles with 2-enoylpyridine N-oxides catalyzed by chiral PYBOX-DIPH-Zn(II) complexes has been developed. The catalyst offers substantial substrate scope and furnished alkylated pyrroles in excellent yields (up to 99%) and enantioselectivities (up to >99% ee).Entities:
Year: 2010 PMID： 19947623 DOI： 10.1021/ol902360b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005