Literature DB >> 19947354

Biochemical biomarkers of oxidative collagen damage.

Y Henrotin1, M Deberg, M Mathy-Hartert, G Deby-Dupont.   

Abstract

Collagens are major constituents of connective tissues in the animal kingdom. During aging and inflammatory-related diseases, the collagen network undergoes oxidation that leads to structural and biochemical alterations within the collagen molecule. Collagen oxidation appears to be a key determinant of aging and a critical physiopathologic mechanism of numerous diseases. Further, the detection of oxidized-collagen peptides seems to be a promising approach for the diagnosis and the prognosis of inflammatory diseases. This chapter reviews the structural and biochemical changes to collagen induced by reactive oxygen and nitrogen species and discusses recent data on the use of collagen-derived biomarkers for measuring oxidative damage.

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Year:  2009        PMID： 19947354     DOI： 10.1016/s0065-2423(09)49002-4

Source DB:  PubMed          Journal:  Adv Clin Chem        ISSN： 0065-2423            Impact factor:   5.394


  5 in total

1.  Coll2-1, Coll2-1NO2 and myeloperoxidase concentrations in the synovial fluid of equine tarsocrural joints affected with osteochondrosis.

Authors:  Denis R Verwilghen; Ann Martens; Evita Busschers; Thierry Franck; Michelle Deberg; Yves Henrotin; Laurent Vanderheyden; Didier Serteyn
Journal:  Vet Res Commun       Date:  2011-06-17       Impact factor: 2.459

2.  The effects of the covalent attachment of 3-(4-hydroxy-3,5-di-tert-butylphenyl) propyl amine to glutaraldehyde pretreated bovine pericardium on structural degeneration, oxidative modification, and calcification of rat subdermal implants.

Authors:  Abigail J Christian; Ivan S Alferiev; Jeanne M Connolly; Harry Ischiropoulos; Robert J Levy
Journal:  J Biomed Mater Res A       Date:  2014-12-28       Impact factor: 4.396

3.  Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis.

Authors:  M L Teoh-Fitzgerald; M P Fitzgerald; W Zhong; R W Askeland; F E Domann
Journal:  Oncogene       Date:  2013-01-14       Impact factor: 9.867

4.  The susceptibility of bioprosthetic heart valve leaflets to oxidation.

Authors:  Abigail J Christian; Hongqiao Lin; Ivan S Alferiev; Jeanne M Connolly; Giovanni Ferrari; Stanley L Hazen; Harry Ischiropoulos; Robert J Levy
Journal:  Biomaterials       Date:  2013-12-18       Impact factor: 12.479

5.  Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities.

Authors:  Yves Henrotin; Xavier Chevalier; Gabriel Herrero-Beaumont; Timothy McAlindon; Ali Mobasheri; Karel Pavelka; Christiane Schön; Harrie Weinans; Hans Biesalski
Journal:  BMC Res Notes       Date:  2013-03-26
  5 in total

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