Literature DB >> 19946570

Neo-Clerodane Diterpenes from Ajuga turkestanica.

Mary H Grace1, Diana M Cheng, Ilya Raskin, Mary Ann Lila.   

Abstract

The ethyl acetate extract of the aerial parts of Ajuga turkestanica afforded 6 neo-clerodane diterpenes, including two novel compounds, 14, 15-dihydroajugachin B (1) and 14-hydro-15-methoxyajugachin B (2), in addition to the known diterpenoids chamaepitin (3), ajugachin B (4), ajugapitin (5) and lupulin A (6). Structures were established through exhaustive NMR spectroscopic analysis and chemical transformation in the case of 1. The full (1)H and (13)C NMR assignment of the C-15 R and S configurations of 14-hydro-15-methoxyajugachin B and chamaepitin were elucidated.

Entities:  

Year:  2008        PMID： 19946570      PMCID： PMC2782872          DOI： 10.1016/j.phytol.2008.03.004

Source DB:  PubMed          Journal:  Phytochem Lett        ISSN： 1874-3900            Impact factor:   1.679


  5 in total

1.  Responses of Spodoptera littoralis larvae to Tunisian plant extracts and to neo-clerodane diterpenoids isolated from Ajuga pseudoiva leaves.

Authors:  H Ben Jannet ; F Harzallah-Skhiri; Z Mighri; M S Simmonds; W M Blaney
Journal:  Fitoterapia       Date:  2000-04       Impact factor: 2.882

Review 2.  Insect antifeedant activity of clerodane diterpenes and related model compounds.

Authors:  Edwin A Klein Gebbinck; Ben J M Jansen; Aede de Groot
Journal:  Phytochemistry       Date:  2002-12       Impact factor: 4.072

3.  Structure-antibacterial activity relationship of secondary metabolites from Ajuga pseudoiva Rob. leaves.

Authors:  Hichem Ben Jannet; Atef Chaari; Amina Bakhrouf; Zine Mighri
Journal:  Nat Prod Res       Date:  2006-03       Impact factor: 2.861

4.  Antibacterial neoclerodane diterpenoids from Ajuga lupulina.

Authors:  H Chen; R X Tan; Z L Liu; Y Zhang; L Yang
Journal:  J Nat Prod       Date:  1996-07       Impact factor: 4.050

5.  Cancer chemopreventive activity of an iridoid glycoside, 8-acetylharpagide, from Ajuga decumbens.

Authors:  T Konoshima; M Takasaki; H Tokuda; H Nishino
Journal:  Cancer Lett       Date:  2000-08-31       Impact factor: 8.679
  5 in total
  1 in total

1.  Computer-Aided Chemotaxonomy and Bioprospecting Study of Diterpenes of the Lamiaceae Family.

Authors:  Andreza Barbosa Silva Cavalcanti; Renata Priscila Costa Barros; Vicente Carlos de Oliveira Costa; Marcelo Sobral da Silva; Josean Fechine Tavares; Luciana Scotti; Marcus Tullius Scotti
Journal:  Molecules       Date:  2019-10-30       Impact factor: 4.411
  1 in total

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