Literature DB >> 19944289

Etiology and treatment of hypogonadism in adolescents.

Vidhya Viswanathan1, Erica A Eugster.   

Abstract

Adequate functioning at all levels of the hypothalamic-pituitary-gonadal axis is necessary for normal gonadal development and subsequent sex steroid production. Deficiencies at any level of the axis can lead to a hypogonadal state. The causes of hypogonadism are heterogeneous and may involve any level of the reproductive system. This review discusses various causes of hypogonadism, describes the evaluation of hypogonadal states, and outlines treatment options for the induction of puberty in affected adolescents. Whereas some conditions are clearly delineated, the exact etiology and underlying pathogenesis of many disorders is unknown.

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Year:  2009        PMID： 19944289      PMCID： PMC4802969          DOI： 10.1016/j.ecl.2009.08.004

Source DB:  PubMed          Journal:  Endocrinol Metab Clin North Am        ISSN： 0889-8529            Impact factor:   4.741


  116 in total

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4.  Biologic effects of transdermal estradiol.

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Journal:  N Engl J Med       Date:  1986-06-19       Impact factor: 91.245

Review 5.  Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa.

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Journal:  Lancet       Date:  2005 Jul 2-8       Impact factor: 79.321

Review 6.  Systematic approach for detection of endocrine disorders in children treated for brain tumors.

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Journal:  Med Pediatr Oncol       Date:  1997-08

7.  Mosaic Turner syndrome: cytogenetics versus FISH.

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Journal:  Ann Hum Genet       Date:  1999-05       Impact factor: 1.670

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Authors:  A Akefeldt; C J Törnhage; C Gillberg
Journal:  Dev Med Child Neurol       Date:  1999-11       Impact factor: 5.449

9.  Hypopituitarism and neurodevelopmental abnormalities in relation to central nervous system structural defects in children with optic nerve hypoplasia.

Authors:  Nadine G Haddad; Erica A Eugster
Journal:  J Pediatr Endocrinol Metab       Date:  2005-09       Impact factor: 1.634

10.  Hypogonadism and pubertal development in Prader-Willi syndrome.

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Journal:  Eur J Pediatr       Date:  2003-02-27       Impact factor: 3.183
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  2 in total

Review 1.  Male reprotoxicity and endocrine disruption.

Authors:  Sarah Campion; Natasha Catlin; Nicholas Heger; Elizabeth V McDonnell; Sara E Pacheco; Camelia Saffarini; Moses A Sandrof; Kim Boekelheide
Journal:  Exp Suppl       Date:  2012

2.  The study design and methodology for the ARCHER study--adolescent rural cohort study of hormones, health, education, environments and relationships.

Authors:  Katharine Steinbeck; Philip Hazell; Robert G Cumming; S Rachel Skinner; Rebecca Ivers; Robert Booy; Greg Fulcher; David J Handelsman; Andrew J Martin; Geoff Morgan; Jean Starling; Adrian Bauman; Margot L Rawsthorne; David L Bennett; Chin Moi Chow; Mary K Lam; Patrick Kelly; Ngiare J Brown; Karen Paxton; Catherine Hawke
Journal:  BMC Pediatr       Date:  2012-09-05       Impact factor: 2.125
  2 in total

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