Literature DB >> 19942608

The conditional independences between variables derived from two independent identically distributed Markov random fields when pairwise order is ignored.

Alun Thomas1.   

Abstract

A result for the equivalence of conditional independence graphs of ordered and unordered vector random variables from first-order Markov models is extended to arbitrary forests. The result is relevant to estimating graphical models for linkage disequilibrium between genetic loci. It explains why, in terms of the conditional independence structure, it sometimes does not matter whether you consider haplotypes or genotypes.

Mesh:

Year:  2009        PMID: 19942608      PMCID: PMC2948832          DOI: 10.1093/imammb/dqp022

Source DB:  PubMed          Journal:  Math Med Biol        ISSN: 1477-8599            Impact factor:   1.854


  8 in total

1.  Graphical modeling of the joint distribution of alleles at associated loci.

Authors:  Alun Thomas; Nicola J Camp
Journal:  Am J Hum Genet       Date:  2004-04-26       Impact factor: 11.025

2.  Characterizing allelic associations from unphased diploid data by graphical modeling.

Authors:  Alun Thomas
Journal:  Genet Epidemiol       Date:  2005-07       Impact factor: 2.135

3.  Bayesian graphical models for genomewide association studies.

Authors:  Claudio J Verzilli; Nigel Stallard; John C Whittaker
Journal:  Am J Hum Genet       Date:  2006-05-30       Impact factor: 11.025

4.  A new multipoint method for genome-wide association studies by imputation of genotypes.

Authors:  Jonathan Marchini; Bryan Howie; Simon Myers; Gil McVean; Peter Donnelly
Journal:  Nat Genet       Date:  2007-06-17       Impact factor: 38.330

5.  A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.

Authors:  Paul Scheet; Matthew Stephens
Journal:  Am J Hum Genet       Date:  2006-02-17       Impact factor: 11.025

6.  Towards linkage analysis with markers in linkage disequilibrium by graphical modelling.

Authors:  Alun Thomas
Journal:  Hum Hered       Date:  2007-04-27       Impact factor: 0.444

7.  Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering.

Authors:  Sharon R Browning; Brian L Browning
Journal:  Am J Hum Genet       Date:  2007-09-21       Impact factor: 11.025

8.  Estimation of graphical models whose conditional independence graphs are interval graphs and its application to modeling linkage disequilibrium.

Authors:  Alun Thomas
Journal:  Comput Stat Data Anal       Date:  2009-03-15       Impact factor: 1.681

  8 in total
  3 in total

1.  Modelling and visualizing fine-scale linkage disequilibrium structure.

Authors:  David Edwards
Journal:  BMC Bioinformatics       Date:  2013-06-06       Impact factor: 3.169

2.  Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.

Authors:  Richard J Binney; Aleksandr Pankov; Gabriel Marx; Xuanzie He; Faye McKenna; Adam M Staffaroni; John Kornak; Suneth Attygalle; Adam L Boxer; Norbert Schuff; Maria-Luisa Gorno-Tempini; Michael W Weiner; Joel H Kramer; Bruce L Miller; Howard J Rosen
Journal:  Brain Behav       Date:  2017-03-23       Impact factor: 2.708

3.  Data-driven regions of interest for longitudinal change in frontotemporal lobar degeneration.

Authors:  Aleksandr Pankov; Richard J Binney; Adam M Staffaroni; John Kornak; Suneth Attygalle; Norbert Schuff; Michael W Weiner; Joel H Kramer; Bradford C Dickerson; Bruce L Miller; Howard J Rosen
Journal:  Neuroimage Clin       Date:  2015-08-18       Impact factor: 4.881

  3 in total

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