Literature DB >> 19942288

Telomerase gene mutation screening in Chinese patients with aplastic anemia.

Bing Han1, Bo Liu, Wei Cui, Xuan Wang, Jie Lin, Yongqiang Zhao.   

Abstract

To study the incidence of telomerase gene mutations in Chinese patients with acquired bone marrow failure (BMF) and explore its relationship with telomere shortening. Blood samples from 66 patients with aplastic anemia (AA) in northern China were collected and TERC mutation analysis was performed. Two TERC mutations were identified. The incidence of telomerase gene mutations in Chinese people with acquired AA is similar to that of the western people. Copyright 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID: 19942288     DOI: 10.1016/j.leukres.2009.11.001

Source DB:  PubMed          Journal:  Leuk Res        ISSN: 0145-2126            Impact factor:   3.156


  7 in total

1.  Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies.

Authors:  Su Lu; Xiaotian Qin; Shaopeng Yuan; Yawei Li; Liming Wang; Yusheng Jin; Gang Zeng; Lawrence Yen; Jenny Hu; Tracie Dang; Sophie Song; Qi Hou; Jianyu Rao
Journal:  Int J Clin Exp Med       Date:  2014-03-15

Review 2.  The complex pathophysiology of acquired aplastic anaemia.

Authors:  Y Zeng; E Katsanis
Journal:  Clin Exp Immunol       Date:  2015-04-23       Impact factor: 4.330

Review 3.  Hematopoietic stem cell development, aging and functional failure.

Authors:  Jichun Chen
Journal:  Int J Hematol       Date:  2011-04-27       Impact factor: 2.490

4.  Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis.

Authors:  Brett Ley; Dara G Torgerson; Justin M Oldham; Ayodeji Adegunsoye; Shuo Liu; Jie Li; Brett M Elicker; Travis S Henry; Jeffrey A Golden; Kirk D Jones; Amy Dressen; Brian L Yaspan; Joseph R Arron; Imre Noth; Thomas J Hoffmann; Paul J Wolters
Journal:  Am J Respir Crit Care Med       Date:  2019-11-01       Impact factor: 21.405

5.  Single-cell transcriptomics identifies premature aging features of TERC-deficient mouse brain and bone marrow.

Authors:  Chunying Yang; Yidan Pang; Yigang Huang; Fang Ye; Xiaoyi Chen; Youshui Gao; Changqing Zhang; Lufeng Yao; Junjie Gao
Journal:  Geroscience       Date:  2022-05-11       Impact factor: 7.713

Review 6.  Genetics of human telomere biology disorders.

Authors:  Patrick Revy; Caroline Kannengiesser; Alison A Bertuch
Journal:  Nat Rev Genet       Date:  2022-09-23       Impact factor: 59.581

7.  Expression of Shelterin component POT1 is associated with decreased telomere length and immunity condition in humans with severe aplastic anemia.

Authors:  Ting Wang; Shu-chong Mei; Rong Fu; Hua-quan Wang; Zong-hong Shao
Journal:  J Immunol Res       Date:  2014-05-06       Impact factor: 4.493

  7 in total

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