OBJECTIVE: To evaluate the risk of high-risk human papillomavirus (HPV) infection in women with Trichomonas vaginalis infection, and the reason remains unclear. METHODS: A total of 40,000 liquid-based cytology specimens were tested from 2005 to 2008. Among these, high-risk HPV testing using the hybrid capture II assay was performed in positive cases of T. vaginalis according to the age of patients (<30 years old, between 30 and 50 years old, more than 50 years old). As controls, HPV detection was also performed in 450 normal smears. RESULTS: T. vaginalis was found in 80 cases (0.2%). From these 80 cases, 57 were available for HPV testing (8 patients <30 years old, 42 patients between 30 and 50 years old and 7 patients more than 50 years old). As controls, high-risk HPV was tested in 150 patients with normal cytology for each of these three age categories. High-risk HPV was significantly more frequently detected in women with T. vaginalis than in women with normal smear irrespective of the categories of age (P < 0.01). CONCLUSION: For the first time, we demonstrated a significant prevalence of high-risk HPV in women with cytological proved T. vaginalis infection independent of the age ranges. Our data suggest a potential association between these two infectious agents by the way of a sexual intercourse and probably by a biochemical or immunological reasons.
OBJECTIVE: To evaluate the risk of high-risk human papillomavirus (HPV) infection in women with Trichomonas vaginalis infection, and the reason remains unclear. METHODS: A total of 40,000 liquid-based cytology specimens were tested from 2005 to 2008. Among these, high-risk HPV testing using the hybrid capture II assay was performed in positive cases of T. vaginalis according to the age of patients (<30 years old, between 30 and 50 years old, more than 50 years old). As controls, HPV detection was also performed in 450 normal smears. RESULTS:T. vaginalis was found in 80 cases (0.2%). From these 80 cases, 57 were available for HPV testing (8 patients <30 years old, 42 patients between 30 and 50 years old and 7 patients more than 50 years old). As controls, high-risk HPV was tested in 150 patients with normal cytology for each of these three age categories. High-risk HPV was significantly more frequently detected in women with T. vaginalis than in women with normal smear irrespective of the categories of age (P < 0.01). CONCLUSION: For the first time, we demonstrated a significant prevalence of high-risk HPV in women with cytological proved T. vaginalis infection independent of the age ranges. Our data suggest a potential association between these two infectious agents by the way of a sexual intercourse and probably by a biochemical or immunological reasons.
Authors: Débora Afonso Silva Rocha; Ivone de Andrade Rosa; Julio A Urbina; Wanderley de Souza; Marlene Benchimol Journal: Parasitol Res Date: 2014-04-22 Impact factor: 2.289
Authors: Christian Heiss; Zhirui Wang; Ian Black; Parastoo Azadi; Raina N Fichorova; Bibhuti N Singh Journal: Carbohydr Res Date: 2015-11-10 Impact factor: 2.104
Authors: Ilka Kassandra Pereira Belfort; Ana Paula Almeida Cunha; Francisco Pedro Belfort Mendes; Leonardo Victor Galvão-Moreira; Renata Gaspar Lemos; Lucas Henrique de Lima Costa; Pablo Monteiro; Mariele Borges Ferreira; Gerusinete Rodrigues Bastos Dos Santos; Joyce Leal Costa; Alice de Sá Ferreira; Luiz Gustavo Oliveira Brito; Luciane Maria Oliveira Brito; Flávia Castello Branco Vidal; Sally Cristina Moutinho Monteiro Journal: BMC Womens Health Date: 2021-04-23 Impact factor: 2.809