Literature DB >> 19940534

Clinicopathological analyses of fifty supracricoid laryngectomized specimens: evidence base supporting minimal margins.

Meijin Nakayama1, Christopher Holsinger, Makito Okamoto, Yutomo Seino, Shunsuke Miyamoto, Masahiko Takeda, Satoru Yokobori, Takashi Masaki, Seiichi Hayashi.   

Abstract

OBJECTIVES: Supracricoid laryngectomy (SCL) is a reliable laryngeal preservation surgery. However, close surgical margins are often inevitable. Based on clinicopathological analyses of supracricoid laryngectomized specimens, we evaluated the evidence base supporting minimal margins.
METHODS: The distance between tumor edge and resected margin was measured macro- and microscopically at the anterior, posterior, superior and inferior edges, using 50 surgical specimens. The margins were correlated with pathological T staging and the prognoses.
RESULTS: The anterior and posterior margins were the shortest, and the superior margin was the longest. The inferior margin was the only edge at which a positive margin was encountered. Cancer extending 10 mm below the glottal free edge significantly decreased the inferior margin.
CONCLUSIONS: The surgical potential of SCL with cricohyoidoepiglottopexy was confirmed to be able to cope with tumor extensions showing margins of a few millimeters at the anterior, posterior and superior ends. Accurate assessment and management at the inferior margin is the key to stable local control. Copyright 2009 S. Karger AG, Basel.

Entities:  

Mesh:

Year:  2009        PMID: 19940534     DOI: 10.1159/000261836

Source DB:  PubMed          Journal:  ORL J Otorhinolaryngol Relat Spec        ISSN: 0301-1569            Impact factor:   1.538


  6 in total

1.  Analysis of multicentricity in supraglottic laryngeal carcinoma treated with partial laryngeal surgery.

Authors:  Ela Cömert; Umit Tunçel; Ziya Sencan
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-09-30       Impact factor: 2.503

2.  Delayed wound infection after supracricoid partial laryngectomy following failure of high dose radiation.

Authors:  Meijin Nakayama; Makito Okamoto; Yutomo Seino; Shunsuke Miyamoto; Takashi Matsuki; Akiko Ogawa
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-08-10       Impact factor: 2.503

3.  Supracricoid laryngectomy with cricohyoidoepiglottopexy (CHEP) in the management of laryngeal carcinoma: oncologic results. A 35-year experience.

Authors:  C Page; G Mortuaire; F Mouawad; O Ganry; J Darras; X Pasquesoone; D Chevalier
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-12-04       Impact factor: 2.503

4.  CO(2) laser versus cold steel margin analysis following endoscopic excision of glottic cancer.

Authors:  Fawaz M Makki; Matthew H Rigby; Martin Bullock; Timothy Brown; Robert D Hart; Jonathan Trites; Michael L Hinni; S Mark Taylor
Journal:  J Otolaryngol Head Neck Surg       Date:  2014-02-06

Review 5.  Evidence and evidence gaps of laryngeal cancer surgery.

Authors:  Susanne Wiegand
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2016-12-15

6.  Assessment of margins in transoral laser and robotic surgery.

Authors:  Yaniv Hamzany; Daniel Brasnu; Thomas Shpitzer; Jacob Shvero
Journal:  Rambam Maimonides Med J       Date:  2014-04-28
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.