P E Wändell1, A C Carlsson, U de Faire, M-L Hellénius. 1. Center for Family and Community Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Alfred Nobels allé 12, SE-14183 Huddinge, Sweden. per.wandell@ki.se
Abstract
BACKGROUND AND AIMS: Some immigrant groups in Sweden show a higher incidence of cardiovascular diseases, especially coronary heart disease. There is a lack of data of pattern of blood lipids among these. The aim of this study was to estimate the prevalence of dyslipidaemia in men and women of foreign-born origin compared to Swedish-born. METHODS AND RESULTS: A cross-sectional study of a random sample of the population in Stockholm County, Sweden, with total of 4228 60-year-old men and women. Medical, lifestyle and socio-economic data were collected by questionnaires, and anthropometric and laboratory data through medical examination. Outcomes were odds ratios (OR) with 95% confidence interval (95% CI) for dyslipidaemia in different groups, with Swedish-born as reference group, with adjustment for anthropometric, medical, lifestyle and socio-economic factors. Among non-European immigrants, the fully adjusted OR of high cholesterol was 0.57 (95% CI 0.37-0.88), of high LDL-cholesterol was 0.62 (95% CI 0.40-0.96), and of low HDL-cholesterol was 2.06 (95% CI 1.35-3.15). When only adjusting for sex, Finnish-born and non-European immigrants showed higher risk of high triglycerides, OR 1.31 (95% CI 1.01-1.71) and OR 1.98 (95% CI 1.34-2.93), respectively, and of high apoB/apoA-I ratio, OR 1.29 (95% CI 1.00-1.66) and OR 1.57 (95% CI 1.06-2.33), respectively. CONCLUSION: The finding of blood lipid disturbances among immigrants in this study partly explain the higher cardiovascular morbidity shown in previous studies. Non-European immigrants showed a different lipid pattern, with lower HDL-cholesterol, which could possibly be of genetic background.
BACKGROUND AND AIMS: Some immigrant groups in Sweden show a higher incidence of cardiovascular diseases, especially coronary heart disease. There is a lack of data of pattern of blood lipids among these. The aim of this study was to estimate the prevalence of dyslipidaemia in men and women of foreign-born origin compared to Swedish-born. METHODS AND RESULTS: A cross-sectional study of a random sample of the population in Stockholm County, Sweden, with total of 4228 60-year-old men and women. Medical, lifestyle and socio-economic data were collected by questionnaires, and anthropometric and laboratory data through medical examination. Outcomes were odds ratios (OR) with 95% confidence interval (95% CI) for dyslipidaemia in different groups, with Swedish-born as reference group, with adjustment for anthropometric, medical, lifestyle and socio-economic factors. Among non-European immigrants, the fully adjusted OR of high cholesterol was 0.57 (95% CI 0.37-0.88), of high LDL-cholesterol was 0.62 (95% CI 0.40-0.96), and of low HDL-cholesterol was 2.06 (95% CI 1.35-3.15). When only adjusting for sex, Finnish-born and non-European immigrants showed higher risk of high triglycerides, OR 1.31 (95% CI 1.01-1.71) and OR 1.98 (95% CI 1.34-2.93), respectively, and of high apoB/apoA-I ratio, OR 1.29 (95% CI 1.00-1.66) and OR 1.57 (95% CI 1.06-2.33), respectively. CONCLUSION: The finding of blood lipid disturbances among immigrants in this study partly explain the higher cardiovascular morbidity shown in previous studies. Non-European immigrants showed a different lipid pattern, with lower HDL-cholesterol, which could possibly be of genetic background.
Authors: Axel C Carlsson; Erik Ingelsson; Johan Sundström; Juan Jesus Carrero; Stefan Gustafsson; Tobias Feldreich; Markus Stenemo; Anders Larsson; Lars Lind; Johan Ärnlöv Journal: Clin J Am Soc Nephrol Date: 2017-07-21 Impact factor: 8.237
Authors: Axel C Carlsson; Tobias E Larsson; Johanna Helmersson-Karlqvist; Anders Larsson; Lars Lind; Johan Ärnlöv Journal: J Am Soc Nephrol Date: 2014-02-07 Impact factor: 10.121
Authors: Axel C Carlsson; Lina Nordquist; Tobias E Larsson; Juan-Jesús Carrero; Anders Larsson; Lars Lind; Johan Ärnlöv Journal: Cardiorenal Med Date: 2015-07-31 Impact factor: 2.041
Authors: Axel C Carlsson; Bengt Starrin; Bruna Gigante; Karin Leander; Mai-Lis Hellenius; Ulf de Faire Journal: BMC Public Health Date: 2014-01-09 Impact factor: 3.295
Authors: B Sjöberg; A R Qureshi; O Heimbürger; P Stenvinkel; L Lind; A Larsson; P Bárány; J Ärnlöv Journal: J Intern Med Date: 2015-09-09 Impact factor: 8.989
Authors: Zayed D Alsharari; Ulf Risérus; Karin Leander; Per Sjögren; Axel C Carlsson; Max Vikström; Federica Laguzzi; Bruna Gigante; Tommy Cederholm; Ulf De Faire; Mai-Lis Hellénius; Matti Marklund Journal: PLoS One Date: 2017-01-26 Impact factor: 3.240
Authors: Axel C Carlsson; Per Wändell; Urban Ösby; Ramin Zarrinkoub; Björn Wettermark; Gunnar Ljunggren Journal: BMC Public Health Date: 2013-07-18 Impact factor: 3.295