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Literature DB >> 19939367

Epigenetics in polycystic ovary syndrome: a pilot study of global DNA methylation.

Ning Xu¹, Ricardo Azziz, Mark O Goodarzi.

Abstract

The percent global methylation of peripheral blood DNA was not significantly altered in 20 women with polycystic ovary syndrome (PCOS) compared with 20 controls. The study of specific tissues and target genomic regions will be required to further determine whether epigenetic alteration influences the development of PCOS. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Biomarkers

Year: 2009 PMID： 19939367 PMCID： PMC2889203 DOI： 10.1016/j.fertnstert.2009.10.020

Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329

23 in total

1. Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome.

Authors: T E Hickey; R S Legro; R J Norman
Journal: J Clin Endocrinol Metab Date: 2006-04-24 Impact factor: 5.958

Review 2. Programming of appetite and type 2 diabetes.

Authors: Malgorzata S Martin-Gronert; Susan E Ozanne
Journal: Early Hum Dev Date: 2005-10-27 Impact factor: 2.079

3. Epigenetic differences arise during the lifetime of monozygotic twins.

Authors: Mario F Fraga; Esteban Ballestar; Maria F Paz; Santiago Ropero; Fernando Setien; Maria L Ballestar; Damia Heine-Suñer; Juan C Cigudosa; Miguel Urioste; Javier Benitez; Manuel Boix-Chornet; Abel Sanchez-Aguilera; Charlotte Ling; Emma Carlsson; Pernille Poulsen; Allan Vaag; Zarko Stephan; Tim D Spector; Yue-Zhong Wu; Christoph Plass; Manel Esteller
Journal: Proc Natl Acad Sci U S A Date: 2005-07-11 Impact factor: 11.205

Review 4. Developmental estrogen exposures predispose to prostate carcinogenesis with aging.

Authors: Gail S Prins; Lynn Birch; Wan-Yee Tang; Shuk-Mei Ho
Journal: Reprod Toxicol Date: 2006-10-24 Impact factor: 3.143

Review 5. Individuality and epigenetics in obesity.

Authors: J Campión; F I Milagro; J A Martínez
Journal: Obes Rev Date: 2009-04-21 Impact factor: 9.213

6. Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: a potential link between epigenetics and schizophrenia.

Authors: Morihiro Shimabukuro; Tsukasa Sasaki; Akira Imamura; Takahiro Tsujita; Chiaki Fuke; Tadashi Umekage; Mamoru Tochigi; Kennichi Hiramatsu; Tetsuji Miyazaki; Takaya Oda; Jun Sugimoto; Yoshihiro Jinno; Yuji Okazaki
Journal: J Psychiatr Res Date: 2006-10-17 Impact factor: 4.791

7. The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome.

Authors: T Hickey; A Chandy; R J Norman
Journal: J Clin Endocrinol Metab Date: 2002-01 Impact factor: 5.958

8. Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4.

Authors: Shuk-Mei Ho; Wan-Yee Tang; Jessica Belmonte de Frausto; Gail S Prins
Journal: Cancer Res Date: 2006-06-01 Impact factor: 12.701

Review 9. Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?

Authors: D H Abbott; D K Barnett; C M Bruns; D A Dumesic
Journal: Hum Reprod Update Date: 2005 Jul-Aug Impact factor: 15.610

Review 10. Review: fetal programming of polycystic ovary syndrome by androgen excess: evidence from experimental, clinical, and genetic association studies.

Authors: Nectaria Xita; Agathocles Tsatsoulis
Journal: J Clin Endocrinol Metab Date: 2006-03-07 Impact factor: 5.958

39 in total

1. Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity.

Authors: Andrea Dunaif
Journal: J Clin Endocrinol Metab Date: 2016-02-23 Impact factor: 5.958

2. Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations.

Authors: Mohan Manikkam; Rebecca Tracey; Carlos Guerrero-Bosagna; Michael K Skinner
Journal: Reprod Toxicol Date: 2012-09-11 Impact factor: 3.143

3. Androgens Regulate Ovarian Gene Expression Through Modulation of Ezh2 Expression and Activity.

Authors: Xiaoting Ma; Emily Hayes; Anindita Biswas; Christina Seger; Hen Prizant; Stephen R Hammes; Aritro Sen
Journal: Endocrinology Date: 2017-09-01 Impact factor: 4.736

4. Developmental programming: Prenatal testosterone-induced changes in epigenetic modulators and gene expression in metabolic tissues of female sheep.

Authors: Xingzi Guo; Muraly Puttabyatappa; Steven E Domino; Vasantha Padmanabhan
Journal: Mol Cell Endocrinol Date: 2020-06-17 Impact factor: 4.102

Review 5. Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome.

Authors: Daniel A Dumesic; Sharon E Oberfield; Elisabet Stener-Victorin; John C Marshall; Joop S Laven; Richard S Legro
Journal: Endocr Rev Date: 2015-10 Impact factor: 19.871

6. Developmental Programming: Contribution of Epigenetic Enzymes to Antral Follicular Defects in the Sheep Model of PCOS.

Authors: Xingzi Guo; Muraly Puttabyatappa; Robert C Thompson; Vasantha Padmanabhan
Journal: Endocrinology Date: 2019-10-01 Impact factor: 4.736

7. Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

Authors: Rebecca Tracey; Mohan Manikkam; Carlos Guerrero-Bosagna; Michael K Skinner
Journal: Reprod Toxicol Date: 2013-01-25 Impact factor: 3.143