Literature DB >> 19939217

8-azapurine nucleus: a versatile scaffold for different targets.

I Giorgi1, V Scartoni.   

Abstract

-Azapurine nucleus is a bioisoster of the purine nucleus. Variously substituted 8-azapurines have been synthesised and studied for their interactions with many enzymes and receptors and for their antitumor and antiviral activity. In this paper the main results of the studies made in these last years on this topic are reported.

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Year:  2009        PMID： 19939217     DOI： 10.2174/138955709789957440

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  5 in total

1.  [Analysis of the clinical features and misdiagnosis reasons of 17 patients misdiagnosed with IgG4-related disease].

Authors:  Z Q Wang; Y Y Liu; X Zhang; T Liu; L M Ren; D H Shen; Y Wang; Z G Li
Journal:  Beijing Da Xue Xue Bao Yi Xue Ban       Date:  2019-12-18

2.  Substituted Purines as High-Affinity Histamine H3 Receptor Ligands.

Authors:  Christian Espinosa-Bustos; Luisa Leitzbach; Tito Añazco; María J Silva; Andrea Del Campo; Alejandro Castro-Alvarez; Holger Stark; Cristian O Salas
Journal:  Pharmaceuticals (Basel)       Date:  2022-05-04

3.  Site-Selective Ribosylation of Fluorescent Nucleobase Analogs Using Purine-Nucleoside Phosphorylase as a Catalyst: Effects of Point Mutations.

Authors:  Alicja Stachelska-Wierzchowska; Jacek Wierzchowski; Agnieszka Bzowska; Beata Wielgus-Kutrowska
Journal:  Molecules       Date:  2015-12-28       Impact factor: 4.411

Review 4.  Syntheses and Applications of 1,2,3-Triazole-Fused Pyrazines and Pyridazines.

Authors:  Gavin R Hoffman; Allen M Schoffstall
Journal:  Molecules       Date:  2022-07-22       Impact factor: 4.927

5.  Excited-State Proton Transfer in 8-Azapurines I: A Kinetic Analysis of 8-Azaxanthine Fluorescence.

Authors:  Jacek Wierzchowski; Bogdan Smyk
Journal:  Molecules       Date:  2020-06-12       Impact factor: 4.411
  5 in total

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