| Literature DB >> 1993757 |
G P Melcher1, K D Reed, M G Rinaldi, J W Lee, P A Pizzo, T J Walsh.
Abstract
Patients with disseminated infections caused by Trichosporon beigelii have a circulating antigen that cross-reacts with the polysaccharide capsule of Cryptococcus neoformans. We studied the localization of this antigen by immunoelectron microscopy in a rabbit model of experimental disseminated trichosporonosis. Deparaffinized lung sections were examined by using a murine monoclonal anti-cryptococcal polysaccharide antibody and colloidal gold particles coated with goat antibody to murine immunoglobulin G. Antigen that cross-reacted with the monoclonal antibody was observed in the T. beigelii cell wall and in a fibrillar matrix extending from the cell wall.Entities:
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Year: 1991 PMID: 1993757 PMCID: PMC269727 DOI: 10.1128/jcm.29.1.192-196.1991
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948