Literature DB >> 19936726

Pharmacogenomic adaptation of antiretroviral therapy: overcoming the failure of lopinavir in an African infant with CYP2D6 ultrarapid metabolism.

Matthias Gorny, Stephanie Röhm, Stephanie Läer, Nezihe Morali, Tim Niehues.   

Abstract

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Year:  2009        PMID： 19936726     DOI： 10.1007/s00228-009-0753-1

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


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  4 in total

1.  CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages.

Authors:  J Kirchheiner; K Brøsen; M L Dahl; L F Gram; S Kasper; I Roots; F Sjöqvist; E Spina; J Brockmöller
Journal:  Acta Psychiatr Scand       Date:  2001-09       Impact factor: 6.392

Review 2.  Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.

Authors:  M Ingelman-Sundberg
Journal:  Pharmacogenomics J       Date:  2005       Impact factor: 3.550

3.  Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction.

Authors:  G N Kumar; J Dykstra; E M Roberts; V K Jayanti; D Hickman; J Uchic; Y Yao; B Surber; S Thomas; G R Granneman
Journal:  Drug Metab Dispos       Date:  1999-08       Impact factor: 3.922

4.  Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

Authors:  G N Kumar; A D Rodrigues; A M Buko; J F Denissen
Journal:  J Pharmacol Exp Ther       Date:  1996-04       Impact factor: 4.030
  4 in total
  3 in total

Review 1.  Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives.

Authors:  Flavia Storelli; Caroline Samer; Jean-Luc Reny; Jules Desmeules; Youssef Daali
Journal:  Clin Pharmacokinet       Date:  2018-10       Impact factor: 6.447

Review 2.  The Impact of Pharmacogenetics on Pharmacokinetics and Pharmacodynamics in Neonates and Infants: A Systematic Review.

Authors:  Nadir Yalçin; Robert B Flint; Ron H N van Schaik; Sinno H P Simons; Karel Allegaert
Journal:  Pharmgenomics Pers Med       Date:  2022-06-30

3.  Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes.

Authors:  Sibongile Tshabalala; Ananyo Choudhury; Natasha Beeton-Kempen; Neil Martinson; Michèle Ramsay; Dalu Mancama
Journal:  Pharmacogenet Genomics       Date:  2019-09       Impact factor: 2.089
  3 in total

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