Literature DB >> 19936723

Telomeres and telomerase as novel drug targets: reflections on the 2009 Nobel Prize in Physiology or Medicine.

Meng Dong, Thomas E Mürdter, Ulrich Klotz.   

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Year:  2009        PMID: 19936723     DOI: 10.1007/s00228-009-0758-9

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


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  21 in total

Review 1.  Natural and pharmacological regulation of telomerase.

Authors:  Jean-Louis Mergny; Jean-François Riou; Patrick Mailliet; Marie-Paule Teulade-Fichou; Eric Gilson
Journal:  Nucleic Acids Res       Date:  2002-02-15       Impact factor: 16.971

2.  Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.

Authors:  Emanuelle Pascolo; Christian Wenz; Joachim Lingner; Norbert Hauel; Henning Priepke; Iris Kauffmann; Pilar Garin-Chesa; Wolfgang J Rettig; Klaus Damm; Andreas Schnapp
Journal:  J Biol Chem       Date:  2002-02-19       Impact factor: 5.157

3.  Effects of telomerase modulation in human hematopoietic progenitor cells.

Authors:  Stefan Zimmermann; Stefanie Glaser; Robin Ketteler; Cornelius F Waller; Ursula Klingmüller; Uwe M Martens
Journal:  Stem Cells       Date:  2004       Impact factor: 6.277

4.  The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity.

Authors:  C W Greider; E H Blackburn
Journal:  Cell       Date:  1987-12-24       Impact factor: 41.582

5.  Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status.

Authors:  Pawel Grabowski; Magnus Hultdin; Karin Karlsson; Gerard Tobin; Anna Aleskog; Ulf Thunberg; Anna Laurell; Christer Sundström; Richard Rosenquist; Göran Roos
Journal:  Blood       Date:  2005-03-03       Impact factor: 22.113

6.  Telomeres shorten during ageing of human fibroblasts.

Authors:  C B Harley; A B Futcher; C W Greider
Journal:  Nature       Date:  1990-05-31       Impact factor: 49.962

7.  Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells.

Authors:  Julia Beisner; Meng Dong; Sebastian Taetz; Noha Nafee; Ernst-Ulrich Griese; Ulrich Schaefer; Claus-Michael Lehr; Ulrich Klotz; Thomas E Mürdter
Journal:  Lung Cancer       Date:  2009-08-19       Impact factor: 5.705

8.  Screening of telomerase inhibitors.

Authors:  Elke Kleideiter; Kamilla Piotrowska; Ulrich Klotz
Journal:  Methods Mol Biol       Date:  2007

9.  Expression of POT1 is associated with tumor stage and telomere length in gastric carcinoma.

Authors:  Tomohiro Kondo; Naohide Oue; Kazuhiro Yoshida; Yoshitsugu Mitani; Kazuhito Naka; Hirofumi Nakayama; Wataru Yasui
Journal:  Cancer Res       Date:  2004-01-15       Impact factor: 12.701

Review 10.  Telomerase and cancer therapeutics.

Authors:  Calvin B Harley
Journal:  Nat Rev Cancer       Date:  2008-03       Impact factor: 60.716

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