Literature DB >> 19936387

The chemistry and biology of LL-37.

Matthew F Burton1, Patrick G Steel.   

Abstract

LL-37 is a human host defence peptide that has a wide range of biological functions, including antimicrobial and immunomodulatory properties. This review summarises how molecular structure influences the balance between the immunomodulatory and antimicrobial functions of LL-37.

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Year:  2009        PMID： 19936387     DOI： 10.1039/b912533g

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  47 in total

1.  OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation of human LL-37.

Authors:  Jenny-Lee Thomassin; John R Brannon; Bernard F Gibbs; Samantha Gruenheid; Hervé Le Moual
Journal:  Infect Immun       Date:  2011-12-05       Impact factor: 3.441

Review 2.  The emerging role of peptides and lipids as antimicrobial epidermal barriers and modulators of local inflammation.

Authors:  N K Brogden; L Mehalick; C L Fischer; P W Wertz; K A Brogden
Journal:  Skin Pharmacol Physiol       Date:  2012-04-26       Impact factor: 3.479

3.  "Click" immobilization on alkylated silicon substrates: model for the study of surface bound antimicrobial peptides.

Authors:  Yan Li; Catherine M Santos; Amit Kumar; Meirong Zhao; Analette I Lopez; Guoting Qin; Alison M McDermott; Chengzhi Cai
Journal:  Chemistry       Date:  2011-01-24       Impact factor: 5.236

Review 4.  Recent advances in alveolar biology: evolution and function of alveolar proteins.

Authors:  Sandra Orgeig; Pieter S Hiemstra; Edwin J A Veldhuizen; Cristina Casals; Howard W Clark; Angela Haczku; Lars Knudsen; Fred Possmayer
Journal:  Respir Physiol Neurobiol       Date:  2010-04-28       Impact factor: 1.931

5.  Receptor-dependent and -independent immunomodulatory effects of phenol-soluble modulin peptides from Staphylococcus aureus on human neutrophils are abrogated through peptide inactivation by reactive oxygen species.

Authors:  Huamei Forsman; Karin Christenson; Johan Bylund; Claes Dahlgren
Journal:  Infect Immun       Date:  2012-03-19       Impact factor: 3.441

Review 6.  Vitamin D3 modulates the innate immune response through regulation of the hCAP-18/LL-37 gene expression and cytokine production.

Authors:  Daniel Svensson; Daniel Nebel; Bengt-Olof Nilsson
Journal:  Inflamm Res       Date:  2015-10-03       Impact factor: 4.575

7.  Differential Regulation of Mas-Related G Protein-Coupled Receptor X2-Mediated Mast Cell Degranulation by Antimicrobial Host Defense Peptides and Porphyromonas gingivalis Lipopolysaccharide.

Authors:  Kshitij Gupta; Chizobam Idahosa; Saptarshi Roy; Donguk Lee; Hariharan Subramanian; Anuradha Dhingra; Kathleen Boesze-Battaglia; Jonathan Korostoff; Hydar Ali
Journal:  Infect Immun       Date:  2017-09-20       Impact factor: 3.441

8.  The antibacterial activity of LL-37 against Treponema denticola is dentilisin protease independent and facilitated by the major outer sheath protein virulence factor.

Authors:  Graciela Rosen; Michael N Sela; Gilad Bachrach
Journal:  Infect Immun       Date:  2011-12-19       Impact factor: 3.441

9.  The antimicrobial peptide LL-37 alters human osteoblast Ca2+ handling and induces Ca2+-independent apoptosis.

Authors:  Johanna Säll; Martin Carlsson; Olof Gidlöf; Anders Holm; Johan Humlén; Jenny Ohman; Daniel Svensson; Bengt-Olof Nilsson; Daniel Jönsson
Journal:  J Innate Immun       Date:  2013-02-13       Impact factor: 7.349

10.  Responses of Candida albicans to the human antimicrobial peptide LL-37.

Authors:  Pei-Wen Tsai; Yin-Lien Cheng; Wen-Ping Hsieh; Chung-Yu Lan
Journal:  J Microbiol       Date:  2014-05-30       Impact factor: 3.422
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