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Literature DB >> 19935768

Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome.

Abstract

Gout is an inflammatory disease caused by the deposition of monosodium urate (MSU) crystals in the joint. Recent studies have significantly advanced our knowledge on the understanding of mechanisms underlying MSU crystal-induced inflammation. MSU crystals act as a 'danger signal' that can be recognized by pattern recognition receptors both at cell surface and cytoplasm, indicating the importance of innate immunity in gout. This review focuses on the critical role of intracellular NALP3 inflammasome in MSU crystal-induced inflammation.

Entities: Chemical Disease Gene Species

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Year: 2009 PMID： 19935768 PMCID： PMC4337950 DOI： 10.1038/icb.2009.93

Source DB: PubMed Journal: Immunol Cell Biol ISSN： 0818-9641 Impact factor: 5.126

41 in total

1. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling.

Authors: Amanda L Gavin; Kasper Hoebe; Bao Duong; Takayuki Ota; Christopher Martin; Bruce Beutler; David Nemazee
Journal: Science Date: 2006-12-22 Impact factor: 47.728

2. Kinetics of IL1 beta mRNA and protein accumulation in human mononuclear cells.

Authors: F S di Giovine; J A Symons; G W Duff
Journal: Immunol Lett Date: 1991-08 Impact factor: 3.685

3. Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation.

Authors: Ru Liu-Bryan; Peter Scott; Anya Sydlaske; David M Rose; Robert Terkeltaub
Journal: Arthritis Rheum Date: 2005-09

4. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.

Authors: Chun-Jen Chen; Yan Shi; Arron Hearn; Kate Fitzgerald; Douglas Golenbock; George Reed; Shizuo Akira; Kenneth L Rock
Journal: J Clin Invest Date: 2006-08 Impact factor: 14.808

5. Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL 1.

Authors: F S Di Giovine; S E Malawista; G Nuki; G W Duff
Journal: J Immunol Date: 1987-05-15 Impact factor: 5.422

Review 6. Pathogenesis of crystal-induced inflammation.

Authors: R C Landis; D O Haskard
Journal: Curr Rheumatol Rep Date: 2001-02 Impact factor: 4.592

7. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils.

Authors: B N Cronstein; Y Molad; J Reibman; E Balakhane; R I Levin; G Weissmann
Journal: J Clin Invest Date: 1995-08 Impact factor: 14.808

8. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.

Authors: Pamela Gasse; Nicolas Riteau; Sabine Charron; Sandra Girre; Lizette Fick; Virginie Pétrilli; Jürg Tschopp; Vincent Lagente; Valérie F J Quesniaux; Bernhard Ryffel; Isabelle Couillin
Journal: Am J Respir Crit Care Med Date: 2009-02-12 Impact factor: 21.405

9. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.

Authors: Hal M Hoffman; Sanna Rosengren; David L Boyle; Jae Y Cho; Jyothi Nayar; James L Mueller; Justin P Anderson; Alan A Wanderer; Gary S Firestein
Journal: Lancet Date: 2004 Nov 13-19 Impact factor: 79.321

10. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study.

Authors: R Terkeltaub; J S Sundy; H R Schumacher; F Murphy; S Bookbinder; S Biedermann; R Wu; S Mellis; A Radin
Journal: Ann Rheum Dis Date: 2009-07-26 Impact factor: 19.103

18 in total

1. Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly.

Authors: Ju Young Bae; Hyun Ho Park
Journal: J Biol Chem Date: 2011-08-31 Impact factor: 5.157

Review 2. Inflammasomes and autoimmunity.

Authors: Patrick J Shaw; Michael F McDermott; Thirumala-Devi Kanneganti
Journal: Trends Mol Med Date: 2010-12-14 Impact factor: 11.951

10. Effects of Modified Simiao Decoction on IL-1 β and TNF α Secretion in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation.

Authors: Ya-Fei Liu; Sheng-Hao Tu; Zhe Chen; Yu Wang; Yong-Hong Hu; Hui Dong
Journal: Evid Based Complement Alternat Med Date: 2014-06-05 Impact factor: 2.629

Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome.

1. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling.

2. Kinetics of IL1 beta mRNA and protein accumulation in human mononuclear cells.

3. Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation.

4. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.

5. Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL 1.

Review 6. Pathogenesis of crystal-induced inflammation.

7. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils.

8. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.

9. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.

10. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study.

1. Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly.

Review 2. Inflammasomes and autoimmunity.

3. Expression of NALP3 in the spleen of mice with portal hypertension.

Review 4. Dangers within: DAMP responses to damage and cell death in kidney disease.

Review 5. Role of melanocortin receptors in the regulation of gouty inflammation.

Review 6. Research progress on the NLRP3 inflammasome and its role in the central nervous system.

Review 7. Uric acid, hyperuricemia and vascular diseases.

8. New and improved strategies for the treatment of gout.

9. Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages.

10. Effects of Modified Simiao Decoction on IL-1 β and TNF α Secretion in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation.