Literature DB >> 19935670

The mechanisms of kinesin motor motility: lessons from the monomeric motor KIF1A.

Nobutaka Hirokawa1, Ryo Nitta, Yasushi Okada.   

Abstract

Most kinesins move processively along microtubules by using energy derived from ATP hydrolysis. Almost all of the intermediate structures of this ATPase reaction cycle have been solved for the monomeric kinesin 3 family motor KIF1A. Based on this structural information, we propose a common mechanism of kinesin motility, focusing on the regulation of kinesin motility through their interaction with microtubules and by their 'neck-linker' region, which connects their motor domain to cargo and kinesin partner heads.

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Year:  2009        PMID： 19935670     DOI： 10.1038/nrm2807

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  60 in total

1.  A structural change in the kinesin motor protein that drives motility.

Authors:  S Rice; A W Lin; D Safer; C L Hart; N Naber; B O Carragher; S M Cain; E Pechatnikova; E M Wilson-Kubalek; M Whittaker; E Pate; R Cooke; E W Taylor; R A Milligan; R D Vale
Journal:  Nature       Date:  1999-12-16       Impact factor: 49.962

2.  Alternate fast and slow stepping of a heterodimeric kinesin molecule.

Authors:  Kuniyoshi Kaseda; Hideo Higuchi; Keiko Hirose
Journal:  Nat Cell Biol       Date:  2003-11-23       Impact factor: 28.824

3.  The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends.

Authors:  Jonne Helenius; Gary Brouhard; Yannis Kalaidzidis; Stefan Diez; Jonathon Howard
Journal:  Nature       Date:  2006-05-04       Impact factor: 49.962

4.  High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations.

Authors:  Masahide Kikkawa; Nobutaka Hirokawa
Journal:  EMBO J       Date:  2006-08-31       Impact factor: 11.598

5.  Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin.

Authors:  Ryo Nitta; Yasushi Okada; Nobutaka Hirokawa
Journal:  Nat Struct Mol Biol       Date:  2008-09-21       Impact factor: 15.369

6.  Bead movement by single kinesin molecules studied with optical tweezers.

Authors:  S M Block; L S Goldstein; B J Schnapp
Journal:  Nature       Date:  1990-11-22       Impact factor: 49.962

7.  Direct observation of kinesin stepping by optical trapping interferometry.

Authors:  K Svoboda; C F Schmidt; B J Schnapp; S M Block
Journal:  Nature       Date:  1993-10-21       Impact factor: 49.962

8.  Influence of the kinesin neck domain on dimerization and ATPase kinetics.

Authors:  W Jiang; M F Stock; X Li; D D Hackney
Journal:  J Biol Chem       Date:  1997-03-21       Impact factor: 5.157

9.  Direct observation of the binding state of the kinesin head to the microtubule.

Authors:  Nicholas R Guydosh; Steven M Block
Journal:  Nature       Date:  2009-08-19       Impact factor: 49.962

10.  Crystal structure of the motor domain of the kinesin-related motor ncd.

Authors:  E P Sablin; F J Kull; R Cooke; R D Vale; R J Fletterick
Journal:  Nature       Date:  1996-04-11       Impact factor: 49.962
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  43 in total

1.  The kinesin superfamily protein KIF17 is regulated by the same transcription factor (NRF-1) as its cargo NR2B in neurons.

Authors:  Shilpa S Dhar; Margaret T T Wong-Riley
Journal:  Biochim Biophys Acta       Date:  2010-12-21

Review 2.  Artificial Molecular Machines.

Authors:  Sundus Erbas-Cakmak; David A Leigh; Charlie T McTernan; Alina L Nussbaumer
Journal:  Chem Rev       Date:  2015-09-08       Impact factor: 60.622

3.  The Aspergillus nidulans CENP-E kinesin KipA is able to dimerize and to move processively along microtubules.

Authors:  Tobias Schunck; Saturnino Herrero; Reinhard Fischer
Journal:  Curr Genet       Date:  2011-07-23       Impact factor: 3.886

4.  Dominant transmission of de novo KIF1A motor domain variant underlying pure spastic paraplegia.

Authors:  Emil Ylikallio; Doyoun Kim; Pirjo Isohanni; Mari Auranen; Eunjoon Kim; Tuula Lönnqvist; Henna Tyynismaa
Journal:  Eur J Hum Genet       Date:  2015-01-14       Impact factor: 4.246

5.  X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.

Authors:  Manatsu Morikawa; Hiroaki Yajima; Ryo Nitta; Shigeyuki Inoue; Toshihiko Ogura; Chikara Sato; Nobutaka Hirokawa
Journal:  EMBO J       Date:  2015-03-16       Impact factor: 11.598

6.  Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.

Authors:  Grayson DuRaine; Todd W Wisner; Paul Howard; David C Johnson
Journal:  J Virol       Date:  2018-09-26       Impact factor: 5.103

Review 7.  Prime movers: the mechanochemistry of mitotic kinesins.

Authors:  Robert A Cross; Andrew McAinsh
Journal:  Nat Rev Mol Cell Biol       Date:  2014-04       Impact factor: 94.444

8.  Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.

Authors:  Yufeng Tong; Wolfram Tempel; Hui Wang; Kaori Yamada; Limin Shen; Guillermo A Senisterra; Farrell MacKenzie; Athar H Chishti; Hee-Won Park
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-05       Impact factor: 11.205

9.  Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis.

Authors:  Yaniv Erlich; Simon Edvardson; Emily Hodges; Shamir Zenvirt; Pramod Thekkat; Avraham Shaag; Talya Dor; Gregory J Hannon; Orly Elpeleg
Journal:  Genome Res       Date:  2011-04-12       Impact factor: 9.043

10.  Motor protein mutations cause a new form of hereditary spastic paraplegia.

Authors:  Andrés Caballero Oteyza; Esra Battaloğlu; Levent Ocek; Tobias Lindig; Jennifer Reichbauer; Adriana P Rebelo; Michael A Gonzalez; Yasar Zorlu; Burcak Ozes; Dagmar Timmann; Benjamin Bender; Günther Woehlke; Stephan Züchner; Ludger Schöls; Rebecca Schüle
Journal:  Neurology       Date:  2014-05-07       Impact factor: 9.910
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