Literature DB >> 1993541

Assessment of major carcinogens and alkaloids in the tobacco and mainstream smoke of USSR cigarettes.

M V Djordjevic1, C W Sigountos, D Hoffmann, K D Brunnemann, M R Kagan, L P Bush, R D Safaev, G A Belitsky, D Zaridze.   

Abstract

Tobacco and mainstream smoke of USSR cigarettes were analyzed for carcinogens. The pH values of suspensions of the tobacco (5.4-5.6) and the nitrate content of the tobaccos (0.4-1.7%) were as expected for flue-cured and sun-cured tobaccos and mixtures thereof. The nicotine levels of the cigarette tobaccos (0.76-0.94%) and total alkaloid content (0.85-1.08%) were relatively low compared with tobaccos used in Western European and US cigarettes. The concentrations of tobacco-specific N-nitrosamines in the cigarette tobaccos were also low (N'-nitrosonornicotine 0.36-0.85 microgram/g) compared with those in bright, oriental and blended cigarette tobaccos in Western countries (0.3-19 microgram/g). The 2 non-filter and 4 filter cigarettes from the USSR had slow burning rates and yielded 14.0-16.7 puffs/cigarette, while puff yields for commercial cigarettes in Western countries average less than or equal to 11 puffs/cigarette. Consequently, tar and benzo(a)pyrene yields in the smoke of all cigarettes as well as nitrosamine yields were high, especially in the smoke of the filter cigarettes. It appears that an increase in the burning rates of these cigarettes should lead to lower smoke yields.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1993541     DOI: 10.1002/ijc.2910470306

Source DB:  PubMed          Journal:  Int J Cancer        ISSN: 0020-7136            Impact factor:   7.396


  4 in total

1.  Application of GC-MS/MS for the analysis of tobacco alkaloids in cigarette filler and various tobacco species.

Authors:  Joseph G Lisko; Stephen B Stanfill; Bryce W Duncan; Clifford H Watson
Journal:  Anal Chem       Date:  2013-02-27       Impact factor: 6.986

2.  Effects of acute cigarette smoke exposure on macrophage kinetics and release of tumour necrosis factor alpha in rats.

Authors:  G P Pessina; L Paulesu; F Corradeschi; E Luzzi; A D Stefano; M Tanzini; G Matteucci; V Bocci
Journal:  Mediators Inflamm       Date:  1993       Impact factor: 4.711

3.  Chemical constituents of tobacco smoke induce the production of interleukin-8 in human bronchial epithelium, 16HBE cells.

Authors:  Guojun Zhou; Weiqiang Xiao; Chengyun Xu; Yajun Hu; Xiaokai Wu; Fangfang Huang; Xinbo Lu; Chunyun Shi; Ximei Wu
Journal:  Tob Induc Dis       Date:  2016-07-19       Impact factor: 2.600

4.  Quantification of nitromethane in mainstream smoke using gas chromatography and tandem mass spectrometry.

Authors:  Juliana Giraldo Junco; Gala M Chapman; Roberto Bravo Cardenas; Clifford H Watson; Liza Valentín-Blasini
Journal:  Toxicol Rep       Date:  2021-02-15
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.