Literature DB >> 19935381

A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro.

Woohyun Yoon1, Ben-Jiang Ma, Jacques Fellay, Wei Huang, Shi-Mao Xia, Ruijun Zhang, Kevin V Shianna, Hua-Xin Liao, Barton F Haynes, David B Goldstein.   

Abstract

A single-nucleotide polymorphism (rs2395029) in the HCP5 gene associated with HLA-B*5701 is correlated with lower HIV-1 viral set point. The two allelic forms of coding region were ectopically expressed in TZM-bl cells for an effect on HIV-1 replication. No significant HIV-1 restriction was observed in the cells with infectivity assays throughout HIV-1 life cycle, suggesting that the association of HCP5 variant with viral control is likely due to HLA-B*5701-related effect or other functional variants in the haplotype or both.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 19935381      PMCID： PMC3652654          DOI： 10.1097/QAD.0b013e32833202f5

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  16 in total

1.  Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.

Authors:  Marcus Altfeld; Marylyn M Addo; Eric S Rosenberg; Frederick M Hecht; Paul K Lee; Martin Vogel; Xu G Yu; Rika Draenert; Mary N Johnston; Daryld Strick; Todd M Allen; Margaret E Feeney; James O Kahn; Rafick P Sekaly; Jay A Levy; Jürgen K Rockstroh; Philip J Goulder; Bruce D Walker
Journal:  AIDS       Date:  2003-12-05       Impact factor: 4.177

2.  Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).

Authors:  Sophie Limou; Sigrid Le Clerc; Cédric Coulonges; Wassila Carpentier; Christian Dina; Olivier Delaneau; Taoufik Labib; Lieng Taing; Rob Sladek; Christiane Deveau; Rojo Ratsimandresy; Matthieu Montes; Jean-Louis Spadoni; Jean-Daniel Lelièvre; Yves Lévy; Amu Therwath; François Schächter; Fumihiko Matsuda; Ivo Gut; Philippe Froguel; Jean-François Delfraissy; Serge Hercberg; Jean-François Zagury
Journal:  J Infect Dis       Date:  2009-02-01       Impact factor: 5.226

3.  A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region.

Authors:  C Vernet; M T Ribouchon; G Chimini; A M Jouanolle; I Sidibé; P Pontarotti
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846

4.  HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.

Authors:  S A Migueles; M S Sabbaghian; W L Shupert; M P Bettinotti; F M Marincola; L Martino; C W Hallahan; S M Selig; D Schwartz; J Sullivan; M Connors
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

5.  Antibody neutralization and escape by HIV-1.

Authors:  Xiping Wei; Julie M Decker; Shuyi Wang; Huxiong Hui; John C Kappes; Xiaoyun Wu; Jesus F Salazar-Gonzalez; Maria G Salazar; J Michael Kilby; Michael S Saag; Natalia L Komarova; Martin A Nowak; Beatrice H Hahn; Peter D Kwong; George M Shaw
Journal:  Nature       Date:  2003-03-20       Impact factor: 49.962

6.  Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection.

Authors:  Daniëlle van Manen; Neeltje A Kootstra; Brigitte Boeser-Nunnink; Muna Am Handulle; Angélique B van't Wout; Hanneke Schuitemaker
Journal:  AIDS       Date:  2009-01-02       Impact factor: 4.177

7.  Activation of the interferon system by short-interfering RNAs.

Authors:  Carol A Sledz; Michelle Holko; Michael J de Veer; Robert H Silverman; Bryan R G Williams
Journal:  Nat Cell Biol       Date:  2003-08-24       Impact factor: 28.824

8.  The role of protective HCP5 and HLA-C associated polymorphisms in the control of HIV-1 replication in a subset of elite suppressors.

Authors:  Yefei Han; Jun Lai; Patricia Barditch-Crovo; Joel E Gallant; Thomas M Williams; Robert F Siliciano; Joel N Blankson
Journal:  AIDS       Date:  2008-02-19       Impact factor: 4.177

9.  Measuring HIV neutralization in a luciferase reporter gene assay.

Authors:  David C Montefiori
Journal:  Methods Mol Biol       Date:  2009

10.  The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys.

Authors:  Matthew Stremlau; Christopher M Owens; Michel J Perron; Michael Kiessling; Patrick Autissier; Joseph Sodroski
Journal:  Nature       Date:  2004-02-26       Impact factor: 49.962
View more
  9 in total

Review 1.  Host genes important to HIV replication and evolution.

Authors:  Amalio Telenti; Welkin E Johnson
Journal:  Cold Spring Harb Perspect Med       Date:  2012-04       Impact factor: 6.915

2.  LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data.

Authors:  Qinghua Jiang; Rui Ma; Jixuan Wang; Xiaoliang Wu; Shuilin Jin; Jiajie Peng; Renjie Tan; Tianjiao Zhang; Yu Li; Yadong Wang
Journal:  BMC Genomics       Date:  2015-01-29       Impact factor: 3.969

Review 3.  Long Noncoding RNA HCP5, a Hybrid HLA Class I Endogenous Retroviral Gene: Structure, Expression, and Disease Associations.

Authors:  Jerzy K Kulski
Journal:  Cells       Date:  2019-05-20       Impact factor: 6.600

Review 4.  Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches.

Authors:  Alessandra Mozzi; Chiara Pontremoli; Manuela Sironi
Journal:  Infect Genet Evol       Date:  2017-09-22       Impact factor: 3.342

5.  Common genetic variation and the control of HIV-1 in humans.

Authors:  Jacques Fellay; Dongliang Ge; Kevin V Shianna; Sara Colombo; Bruno Ledergerber; Elizabeth T Cirulli; Thomas J Urban; Kunlin Zhang; Curtis E Gumbs; Jason P Smith; Antonella Castagna; Alessandro Cozzi-Lepri; Andrea De Luca; Philippa Easterbrook; Huldrych F Günthard; Simon Mallal; Cristina Mussini; Judith Dalmau; Javier Martinez-Picado; José M Miro; Niels Obel; Steven M Wolinsky; Jeremy J Martinson; Roger Detels; Joseph B Margolick; Lisa P Jacobson; Patrick Descombes; Stylianos E Antonarakis; Jacques S Beckmann; Stephen J O'Brien; Norman L Letvin; Andrew J McMichael; Barton F Haynes; Mary Carrington; Sheng Feng; Amalio Telenti; David B Goldstein
Journal:  PLoS Genet       Date:  2009-12-24       Impact factor: 5.917

6.  Immunogenetics: Genome-Wide Association of Non-Progressive HIV and Viral Load Control: HLA Genes and Beyond.

Authors:  Sophie Limou; Jean-François Zagury
Journal:  Front Immunol       Date:  2013-05-27       Impact factor: 7.561

7.  LncRNApred: Classification of Long Non-Coding RNAs and Protein-Coding Transcripts by the Ensemble Algorithm with a New Hybrid Feature.

Authors:  Cong Pian; Guangle Zhang; Zhi Chen; Yuanyuan Chen; Jin Zhang; Tao Yang; Liangyun Zhang
Journal:  PLoS One       Date:  2016-05-26       Impact factor: 3.240

8.  MHC Class I Regulation: The Origin Perspective.

Authors:  Alicja Sznarkowska; Sara Mikac; Magdalena Pilch
Journal:  Cancers (Basel)       Date:  2020-05-04       Impact factor: 6.639

9.  Profiles of Long Non-Coding RNAs and mRNA Expression in Human Macrophages Regulated by Interleukin-27.

Authors:  Xiaojun Hu; Suranjana Goswami; Ju Qiu; Qian Chen; Sylvain Laverdure; Brad T Sherman; Tomozumi Imamichi
Journal:  Int J Mol Sci       Date:  2019-12-09       Impact factor: 5.923
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.