Literature DB >> 19934544

Serological and genetic analysis of leptospirosis in patients with acute febrile illness in kandy, sri lanka.

Nobuo Koizumi1, Chandika D Gamage, Maki Muto, Senanayake A M Kularatne, B D Budagoda, R P Rajapakse, Hidehiko Tamashiro, Haruo Watanabe.   

Abstract

Leptospirosis has emerged as an important infectious disease in Sri Lanka and little information is available on circulating leptospiral species and serogroups in this country. Therefore, we studied circulating leptospiral species and serogroups in patients with acute febrile illness using polymerase chain reaction and the microscopic agglutination test, respectively. Anti-leptospiral antibodies were detected in 26 of 107 serum samples studied (24.3%). The predominant reacting serogroups were Sejroe (9/26, 34.6%) and Icterohaemorrhagiae (5/26, 19.2%). Leptospiral DNA was detected in 3 of the 107 serum samples. The deduced leptospiral species were Leptospira interrogans and L. kirschneri (2 and 1 samples, respectively). These results confirm the existence of a wide array of leptospiral species and serogroups in Sri Lanka and would help to thoroughly elucidate the epidemiology of leptospirosis in this country.

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Year:  2009        PMID: 19934544

Source DB:  PubMed          Journal:  Jpn J Infect Dis        ISSN: 1344-6304            Impact factor:   1.362


  8 in total

1.  Redefining Gold Standard Testing for Diagnosing Leptospirosis: Further Evidence from a Well-Characterized, Flood-Related Outbreak in Sri Lanka.

Authors:  Suneth B Agampodi; Niroshan J Dahanayaka; Karsten Nöckler; Anne Mayer-Scholl; Joseph M Vinetz
Journal:  Am J Trop Med Hyg       Date:  2016-07-11       Impact factor: 2.345

2.  Leptospirosis outbreak in Sri Lanka in 2008: lessons for assessing the global burden of disease.

Authors:  Suneth B Agampodi; Sharon J Peacock; Vasanthi Thevanesam; Danaseela B Nugegoda; Lee Smythe; Janjira Thaipadungpanit; Scott B Craig; Mary Ann Burns; Michael Dohnt; Siriphan Boonsilp; Thamarasi Senaratne; Athula Kumara; Paba Palihawadana; Sahan Perera; Joseph M Vinetz
Journal:  Am J Trop Med Hyg       Date:  2011-09       Impact factor: 2.345

3.  Comparison of two multilocus sequence based genotyping schemes for Leptospira species.

Authors:  Ahmed Ahmed; Janjira Thaipadungpanit; Siriphan Boonsilp; Vanaporn Wuthiekanun; Kishore Nalam; Brian G Spratt; David M Aanensen; Lee D Smythe; Niyaz Ahmed; Edward J Feil; Rudy A Hartskeerl; Sharon J Peacock
Journal:  PLoS Negl Trop Dis       Date:  2011-11-08

4.  Nucleic acid and antigen detection tests for leptospirosis.

Authors:  Bada Yang; Sophia G de Vries; Ahmed Ahmed; Benjamin J Visser; Ingeborg M Nagel; René Spijker; Martin P Grobusch; Rudy A Hartskeerl; Marga Ga Goris; Mariska Mg Leeflang
Journal:  Cochrane Database Syst Rev       Date:  2019-08-01

5.  Regional differences of leptospirosis in Sri Lanka: observations from a flood-associated outbreak in 2011.

Authors:  Suneth B Agampodi; Niroshan J Dahanayaka; Anoma K Bandaranayaka; Manoj Perera; Sumudu Priyankara; Prasanna Weerawansa; Michael A Matthias; Joseph M Vinetz
Journal:  PLoS Negl Trop Dis       Date:  2014-01-16

6.  Laboratory diagnostic, epidemiological, and clinical characteristics of human leptospirosis in Okinawa Prefecture, Japan, 2003-2020.

Authors:  Tetsuya Kakita; Sho Okano; Hisako Kyan; Masato Miyahira; Katsuya Taira; Emi Kitashoji; Nobuo Koizumi
Journal:  PLoS Negl Trop Dis       Date:  2021-12-14

7.  Clinical spectrum of endemic leptospirosis in relation to cytokine response.

Authors:  Niroshana J Dahanayaka; Suneth B Agampodi; Indika Seneviratna; Janith Warnasekara; Rukman Rajapakse; Kosala Ranathunga; Michael Matthias; Joseph M Vinetz
Journal:  PLoS One       Date:  2021-12-08       Impact factor: 3.240

8.  Long term outcome of acute kidney injury due to leptospirosis? A longitudinal study in Sri Lanka.

Authors:  Nalaka J Herath; Senanayake A M Kularatne; Kosala G A D Weerakoon; Abdul Wazil; Nilakshi Subasinghe; Neelakanthi V I Ratnatunga
Journal:  BMC Res Notes       Date:  2014-06-25
  8 in total

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