Literature DB >> 19934073

Urgent action needed to improve vitamin D status among older people in England!

Vasant Hirani1, Kerina Tull, Ayesha Ali, Jennifer Mindell.   

Abstract

BACKGROUND: the importance of vitamin D for bone health is well known, but emerging evidence also suggests that adequate vitamin D status may also be protective against non-communicable diseases. In the UK, government initiatives highlighting the importance of adequate vitamin D among older people have been in place since 1998.
OBJECTIVES: the aim of this analysis is to assess vitamin D status in people aged > or =65, living in private households in England, 2005 and make comparisons with the Health Survey for England (HSE) 2000 and the National Diet and Nutrition Survey (NDNS), 1994. We also examine associations of hypovitaminosis D [serum 25(OH)D <50 nmol/l] with demographic, geographic, lifestyle and health risk factors. DESIGN AND
SETTING: a nationally representative sample of older people living in England in 2005. PARTICIPANTS: 2,070 adults aged > or =65, living in private households taking part in the HSE 2005.
RESULTS: in the HSE 2005, mean serum 25(OH)D levels were 53 and 49 nmol/l in men and women, respectively, these levels are significantly lower than currently recommended at > or =75 nmol/l. Prevalence of vitamin D deficiency [25(OH)D <25 nmol/l] in people aged > or =65 in 2005 was 13% in women and 8% in men. Nearly two thirds (57%) of women and half of men (49%) had serum 25(OH)D <50 nmol/l. Only 16% of men and 13% of women aged > or =65 years had serum 25(OH)D levels > or =75 nmol/l. There is no improvement in vitamin D status in 2005 compared to 2000 and a significant decline in vitamin D status among men in 2005 in comparison to the 1994/1995 NDNS results. The odds of hypovitaminosis D increased by age group from those aged 75-79 to aged > or =85. Season of taking a blood sample, obesity, dark skin pigmentation, not taking vitamin supplements, cigarette smoking, poor general health and longstanding illness were all significant predictors (P < 0.05) of serum 25(OH)D status in adjusted regression models.
CONCLUSIONS: poor vitamin D status of older people continues to be a public health problem in England. Hypovitaminosis D is associated with many risk factors and poor health outcomes. There is now an urgent need for a uniform policy on assessment and dietary supplementation of vitamin D in older people to prevent poor vitamin D status and its negative consequences.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19934073     DOI: 10.1093/ageing/afp195

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  17 in total

1.  High latitude and marine diet: vitamin D status in elderly Faroese.

Authors:  Christine Dalgård; Maria Skaalum Petersen; Anne V Schmedes; Ivan Brandslund; Pal Weihe; Philippe Grandjean
Journal:  Br J Nutr       Date:  2010-05-05       Impact factor: 3.718

2.  Vitamin D deficiency remains prevalent despite increased laboratory testing in New South Wales, Australia.

Authors:  Paul Quaggiotto; Huy Tran; Marie Bhanugopan
Journal:  Singapore Med J       Date:  2014-05       Impact factor: 1.858

3.  Vitamin D, cognitive dysfunction and dementia in older adults.

Authors:  Andy P Dickens; Iain A Lang; Kenneth M Langa; Katarina Kos; David J Llewellyn
Journal:  CNS Drugs       Date:  2011-08       Impact factor: 5.749

4.  The clinical significance of 25OH-Vitamin D status in celiac disease.

Authors:  Aaron Lerner; Yinon Shapira; Nancy Agmon-Levin; Avi Pacht; Dana Ben-Ami Shor; Hoyos Marcus López; Maria Sanchez-Castanon; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2012-06       Impact factor: 8.667

Review 5.  Vitamin D in chronic heart failure.

Authors:  Miles D Witham
Journal:  Curr Heart Fail Rep       Date:  2011-06

Review 6.  Optimal management of sarcopenia.

Authors:  Louise A Burton; Deepa Sumukadas
Journal:  Clin Interv Aging       Date:  2010-09-07       Impact factor: 4.458

7.  The influence of renal function on vitamin D metabolism in the very elderly.

Authors:  G Van Pottelbergh; C Matheï; B Vaes; W Adriaensen; D Gruson; J M Degryse
Journal:  J Nutr Health Aging       Date:  2013-02       Impact factor: 4.075

8.  Circadian rhythm and cartilage extracellular matrix genes in osseointegration: a genome-wide screening of implant failure by vitamin D deficiency.

Authors:  Cristiane Machado Mengatto; Federico Mussano; Yoshitomo Honda; Christopher S Colwell; Ichiro Nishimura
Journal:  PLoS One       Date:  2011-01-11       Impact factor: 3.240

9.  Sex-specific determinants of serum 25-hydroxyvitamin D3 concentrations in an elderly German cohort: a cross-sectional study.

Authors:  Alexandra Jungert; Monika Neuhäuser-Berthold
Journal:  Nutr Metab (Lond)       Date:  2015-01-14       Impact factor: 4.169

10.  The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study.

Authors:  Aaron Leong; Waheed Rehman; Zari Dastani; Celia Greenwood; Nicholas Timpson; Lisa Langsetmo; Claudie Berger; Lei Fu; Betty Y L Wong; Suneil Malik; Rainer Malik; David A Hanley; David E C Cole; David Goltzman; J Brent Richards
Journal:  PLoS Med       Date:  2014-10-28       Impact factor: 11.069

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.