Literature DB >> 19932276

Intrathoracic extramedullary haematopoiesis manifested as a neoplastic lesion within anterior mediastinum.

Mario Santini1, Alfonso Fiorelli, Giovanni Vicidomini, Filomena Napolitano.   

Abstract

Intrathoracic extramedullary hematopoiesis (EMH), the formation of apparently normal blood cells outside the confines of the bone marrow, is an uncommon but well-defined entity. It is usually associated with hematologic disorders and located in the lower paravertebral sulci or rarely in the pleura. We report a case of EMH, which presented in a patient without hematologic disorders and was manifested as an anterior mediastinal mass. The first interesting aspect of our case was that EMH occurred in a patient with normal laboratory findings and no past medical history of anemia. The second remarkable characteristic was that EMH manifested as an anterior mediastinal mass, mimicking a neoplastic lesion. Definitive diagnosis of EMH was established by a video-assisted thoracoscopic surgical biopsy. In light of this diagnosis, no further surgical procedure was carried out.

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Mesh:

Year:  2009        PMID: 19932276     DOI: 10.1016/j.athoracsur.2009.05.042

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  4 in total

1.  [Fine-needle aspiration cell pathology for diagnosis of intrathoracic extramedullary hematopoiesis presenting as a posterior mediastinal tumor: a case report].

Authors:  Jie Zhou; Tong Zhao; Min Deng
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-05-20

2.  Extramedullary hematopoiesis in gastric wall under early gastric cancer in a man with a myeloproliferative disorder: a case report.

Authors:  Dai Kimura; Jun Nakayama; Takaomi Hanaoka; Takashi Muraki; Yasunobu Takeoka; Reina Nakamura; Ayako Nakamura; Shugo Takahata; Naoki Ishizaka; Hiroaki Motoyama
Journal:  J Surg Case Rep       Date:  2022-07-16

3.  Pulmonary extramedullary hematopoiesis involving the pulmonary artery.

Authors:  Varun Monga; Margarida Silverman
Journal:  Hematol Rep       Date:  2015-03-24

Review 4.  An overview on the differential diagnostics of tumors of the anterior-superior mediastinum: the pathologist's perspective.

Authors:  Mirella Marino; Stefano Ascani
Journal:  Mediastinum       Date:  2019-02-22
  4 in total

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