Literature DB >> 199317

The mechanism of actions of collagenase on the inhibition of release of acetylcholine from synaptosomal preparations.

G P Sgaragli, I Sen, A Baba, R A Schulz, J R Cooper.   

Abstract

The release of acetylcholine from synaptosomal preparations from bovine superior cervical ganglia and rat cortex was inhibited when the preparations were pretreated with collagenase. The inhibition of release could be overcome with the calcium ionophore A23187. Collagenase treatment was shown to inhibit the uptake of calcium into the preparations. In addition, gel electrophoresis of synaptosomal membranes revealed two missing high molecular weight proteins when either synaptosomes or synaptosomal membranes were incubated with collagenase.

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Year:  1977        PMID: 199317     DOI: 10.1016/0006-8993(77)90929-5

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  9 in total

1.  Actions of a monoclonal antibody Tor 23 on rat brain presynaptic cholinergic processes.

Authors:  S M Evans; P D Kushner; E M Meyer
Journal:  Neurochem Res       Date:  1993-03       Impact factor: 3.996

2.  Role of synaptosomal Na-accumulation in transmitter release.

Authors:  E M Meyer; J R Cooper
Journal:  Neurochem Res       Date:  1984-06       Impact factor: 3.996

3.  Acetylation and phosphorylation of choline following high or low affinity uptake by rat cortical synaptosomes.

Authors:  E M Meyer; D A Engel; J R Cooper
Journal:  Neurochem Res       Date:  1982-06       Impact factor: 3.996

4.  Dipalmitoylphosphatidylcholine liposomes inhibit calcium-dependent [3H]acetylcholine release.

Authors:  D F Bottiglieri; E M Meyer
Journal:  Neurochem Res       Date:  1987-08       Impact factor: 3.996

5.  Effects of collagenase on the release of [3H]-noradrenaline from bovine cultured adrenal chromaffin cells.

Authors:  G Almazan; D Aunis; A G García; C Montiel; G P Nicolás; P Sánchez-García
Journal:  Br J Pharmacol       Date:  1984-04       Impact factor: 8.739

6.  Dipalmitoylphosphatidylcholine liposomes reduce [3H]acetylcholine levels in an eserine-sensitive manner in rat cerebral cortical synaptosomes.

Authors:  D Bottiglieri; E M Meyer
Journal:  Neurochem Res       Date:  1989-02       Impact factor: 3.996

7.  Insulin receptors in the brain: structural and physiological characterization.

Authors:  M K Raizada; J Shemer; J H Judkins; D W Clarke; B A Masters; D LeRoith
Journal:  Neurochem Res       Date:  1988-04       Impact factor: 3.996

8.  Effects of phorbol esters and a calcium ionophore on angiotensin II binding in rat brain synaptosomes.

Authors:  L M Myers; M K Raizada; C Sumners
Journal:  Neurochem Res       Date:  1989-01       Impact factor: 3.996

9.  Effects of different secretagogues and intracellular messengers on the muscarinic modulation of [3H]acetylcholine release.

Authors:  E S Onge; D A Otero; D F Bottiglieri; E M Meyer
Journal:  Neurochem Res       Date:  1986-11       Impact factor: 3.996

  9 in total

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